Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21470623 | 0.83 | ESR2 (0.56) | NR1H2SMN1; SMN2ESR2NPC1POLB | |
| SCHEMBL21470624 | 0.83 | ESR2 (0.56) | NR1H2SMN1; SMN2ESR2NPC1POLB | |
| SCHEMBL30710500 | 0.83 | TRPM8 (0.41) | NR1H2UCHL1USP30MAPK1KMT2A | |
| SCHEMBL30710404 | 0.83 | LMNA (0.42) | NR1H2UCHL1USP30ESR2HDAC1 | |
| SCHEMBL30710250 | 0.83 | LMNA (0.42) | NR1H2UCHL1USP30ESR2HDAC1 | |
| SCHEMBL24528815 | 0.82 | NR1H2 (0.45) | NR1H2SMN1; SMN2UCHL1USP30ESR2 | |
| SCHEMBL21235427 | 0.82 | ESR2 (0.46) | NR1H2SMN1; SMN2USP30ESR2NPC1 | |
| SCHEMBL30878523 | 0.82 | NR1H2 (0.45) | NR1H2SMN1; SMN2UCHL1USP30ESR2 | |
| SCHEMBL18995111 | 0.82 | ESR2 (0.46) | NR1H2SMN1; SMN2USP30ESR2NPC1 | |
| SCHEMBL3353443 | 0.82 | MAPK1 (0.43) | NR1H2SMN1; SMN2UCHL1USP30POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206852-A | Plasma kallikrein inhibitors | 卡尔维斯塔制药有限公司 | 2022-03-18 | — | — | CN | disclosed |