Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.86 |
| ▸ | MAPT | P10636 | 3/20 | 0.86 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.86 |
| ▸ | MMP1 | P03956 | 3/20 | 0.86 |
| ▸ | SRC | P12931 | 3/20 | 0.86 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.86 |
| ▸ | POLB | P06746 | 2/20 | 0.86 |
| ▸ | GAA | P10253 | 2/20 | 0.86 |
| ▸ | HPGD | P15428 | 2/20 | 0.86 |
| ▸ | RECQL | P46063 | 2/20 | 0.86 |
| ▸ | APP | P05067 | 2/20 | 0.86 |
| ▸ | LCK | P06239 | 2/20 | 0.86 |
| ▸ | TTR | P02766 | 2/20 | 0.86 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.86 |
| ▸ | KDM1A | O60341 | 1/20 | 0.86 |
| ▸ | USP2 | O75604 | 1/20 | 0.86 |
| ▸ | JUN | P05412 | 1/20 | 0.86 |
| ▸ | FYN | P06241 | 1/20 | 0.86 |
| ▸ | THRB | P10828 | 1/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clinopodic Acid A SCHEMBL31488556 | 0.93 | MMP1 (0.86) | TDP1KDM4EMAPTHSD17B10MMP1 | |
| Rosmarinic Acid SCHEMBL29371115 | 0.93 | TDP1 (1.00) | TDP1KDM4EMAPTHSD17B10MMP1 | |
| Rosmarinic Acid SCHEMBL29482753 | 0.93 | TDP1 (1.00) | TDP1KDM4EMAPTHSD17B10MMP1 | |
| Rosmarinic Acid SCHEMBL29438187 | 0.93 | TDP1 (1.00) | TDP1KDM4EMAPTHSD17B10MMP1 | |
| Rosmarinic Acid SCHEMBL7458453 | 0.93 | TDP1 (1.00) | TDP1KDM4EMAPTHSD17B10MMP1 | |
| Rosmarinic Acid SCHEMBL15263387 | 0.93 | TDP1 (1.00) | TDP1KDM4EMAPTHSD17B10MMP1 | |
| Rosmarinic Acid SCHEMBL19348 | 0.93 | TDP1 (1.00) | TDP1KDM4EMAPTHSD17B10MMP1 | |
| Rosmarinic Acid SCHEMBL1650675 | 0.93 | TDP1 (1.00) | TDP1KDM4EMAPTHSD17B10MMP1 | |
| Rosmarinic Acid SCHEMBL15263386 | 0.93 | TDP1 (1.00) | TDP1KDM4EMAPTHSD17B10MMP1 | |
| Rosmarinic Acid SCHEMBL29453379 | 0.93 | TDP1 (1.00) | TDP1KDM4EMAPTHSD17B10MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118272328-A | Caffeoyl-CoA ligase mutant protein, encoding gene, recombinant vector, recombinant bacterium and application thereof | 扬州大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-111132688-B | Cyclosporin analogues and uses thereof | 西普拉里斯有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-116964133-A | Condensation curable composition comprising a siloxane-imide crosslinker | 迈图高新材料公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116888194-A | Condensation curable composition comprising a siloxane-imide base polymer | 迈图高新材料公司 | 2023-10-13 | — | — | CN | disclosed |
| US-20230312471-A1 | CHEMICAL PROBES AND INHIBITORS FOR POLYPEPTIDES OF SARS CORONAVIRUSES | Universität Konstanz (DE) | 2023-10-05 | — | — | US | disclosed |
| EP-4204089-A1 | CHEMICAL PROBES AND INHIBITORS FOR POLYPEPTIDES OF SARS CORONAVIRUSES | Universität Konstanz (DE) | 2023-07-05 | — | — | EP | disclosed |
| CN-116350598-A | Film forming composition for vitamin D drugs, pharmaceutical preparation and preparation method thereof | 人福普克药业（武汉）有限公司 | 2023-06-30 | — | — | CN | disclosed |
| WO-2022043435-A1 | CHEMICAL PROBES AND INHIBITORS FOR POLYPEPTIDES OF SARS CORONAVIRUSES | Universität Konstanz (DE) | 2022-03-03 | — | — | WO | disclosed |
| EP-3960239-A1 | PROTEASES INHIBITORS FOR USE IN THE TREATMENT OF INFECTIONS CAUSED BY SARS CORONAVIRUSES | Universität Konstanz (DE) | 2022-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312471-A1 | CHEMICAL PROBES AND INHIBITORS FOR POLYPEPTIDES OF SARS CORONAVIRUSES | SARS1, ACE, ACE2 | TDP1 2007/4885KDM4E 3340/4885MAPT 2075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.