SCHEMBL29405776

SCHEMBL29405776

C[C@@H](O)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)CCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 5/20 0.61
▸ IL23R Q5VWK5 8/20 0.57
▸ KISS1R Q969F8 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30276253 0.92 GHSR (0.64) GHSRIL23RKISS1R
SCHEMBL29551293 0.92 GHSR (0.64) GHSRIL23RKISS1R
SCHEMBL30276276 0.91 GHSR (0.63) GHSRIL23RKISS1R
SCHEMBL30276219 0.89 GHSR (0.61) GHSRIL23R
SCHEMBL30276201 0.89 GHSR (0.60) GHSRIL23R
SCHEMBL29550892 0.89 GHSR (0.62) GHSRIL23RKISS1R
SCHEMBL30276275 0.88 GHSR (0.60) GHSRIL23RKISS1R
SCHEMBL30276259 0.88 GHSR (0.60) GHSRIL23RKISS1R
SCHEMBL29359135 0.88 KISS1R (0.62) GHSRIL23RKISS1R
SCHEMBL29565376 0.88 GHSR (0.61) GHSRIL23RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11261215-B2 Somatostatin prodrugs YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2022-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11261215-B2 Somatostatin prodrugs VIP, SSTR4, SSTR5 GHSR 18/4885IL23R 2061/4885KISS1R 75/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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