Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29406487 | 0.90 | GPR35 (0.34) | HTTALDH1A1POLBVCAM1MAPT | |
| SCHEMBL2815785 | 0.76 | MAPT (0.47) | ALDH1A1POLBVCAM1MAPTLMNA | |
| SCHEMBL20328777 | 0.75 | TSHR (0.53) | HTTALDH1A1POLBMAPTKMT2A | |
| SCHEMBL29406469 | 0.74 | ALDH1A1 (0.40) | HTTALDH1A1POLBVCAM1MAPT | |
| SCHEMBL26695927 | 0.74 | CYP19A1 (0.38) | HTTALDH1A1VCAM1GPR35MAPK1 | |
| SCHEMBL30733364 | 0.74 | CYP19A1 (0.38) | HTTALDH1A1VCAM1GPR35MAPK1 | |
| SCHEMBL29406579 | 0.72 | MEN1 (0.40) | ALDH1A1POLBMAPTLMNAMEN1 | |
| SCHEMBL44775 | 0.72 | MAPK1 (0.51) | HTTALDH1A1POLBVCAM1MAPT | |
| SCHEMBL17395909 | 0.72 | TDP1 (0.51) | HTTALDH1A1POLBVCAM1MAPT | |
| SCHEMBL29404173 | 0.72 | HTT (0.40) | HTTALDH1A1MAPTMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022053567-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-03-17 | — | — | WO | disclosed |