SCHEMBL29406972

SCHEMBL29406972

Cc1cc(O)nc(O)c1C#N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.46
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
UPP1 Q16831 1/20 0.43
RECQL P46063 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
LMNA P02545 1/20 0.41
ALDH1A1 P00352 6/20 0.40
HPGD P15428 4/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2C19 P33261 2/20 0.39
HSD17B10 Q99714 3/20 0.39
HTT P42858 1/20 0.38
MAPT P10636 2/20 0.37
ALOX15 P16050 1/20 0.37
APOBEC3G Q9HC16 1/20 0.37
HAVCR2 Q8TDQ0 1/20 0.37
POLB P06746 2/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1222275 1.00 KDM4E (0.46) KDM4EMEN1KMT2AUPP1RECQL
SCHEMBL4071512 0.85 L3MBTL1 (0.46) KDM4EMEN1KMT2AUPP1RECQL
SCHEMBL2673578 0.83 KDM4E (0.60) KDM4EMEN1KMT2ARECQLSMN1; SMN2
SCHEMBL31261994 0.83 KDM4E (0.60) KDM4EMEN1KMT2ARECQLSMN1; SMN2
SCHEMBL1625883 0.83 KDM4E (0.46) KDM4EMEN1KMT2AUPP1RECQL
SCHEMBL16576951 0.80 KDM4E (0.43) KDM4EMEN1KMT2AUPP1RECQL
SCHEMBL15539469 0.79 KDM4E (0.30) KDM4EMAPT
SCHEMBL14966612 0.76 ALDH1A1 (0.44) KDM4EMEN1KMT2AUPP1RECQL
SCHEMBL8183612 0.76 KDM4E (0.43) KDM4EMEN1KMT2AUPP1RECQL
SCHEMBL28240790 0.75 TRPV4 (0.43) KDM4EMEN1KMT2AALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120865078-A 2, 6-Dichloro-3-cyano-4-methylpyridine and preparation method thereof 湖北珈兴新材料科技有限公司 2025-10-31 CN disclosed
CN-112694608-B Six-arm polyethylene glycol derivative, preparation method and modified biological related substance 厦门赛诺邦格生物科技股份有限公司 2024-07-02 CN disclosed
CN-115010915-B Nitrogen-branched nine-arm polyethylene glycol derivative, preparation method and modified biologically-relevant substance thereof 厦门赛诺邦格生物科技股份有限公司 2024-06-11 CN disclosed
CN-115010915-A Nitrogen branched nine-arm polyethylene glycol derivative, preparation method and biological related substance modified by nitrogen branched nine-arm polyethylene glycol derivative 厦门赛诺邦格生物科技股份有限公司 2022-09-06 CN disclosed
CN-112834643-B Method for measuring 2, 6-dihydroxy-4-methylpyridine and 2, 6-dihydroxy-3-cyano-4-methylpyridine 郑州原理生物科技有限公司 2022-03-18 CN disclosed