⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64925 | 1.00 | — | — | |
| SCHEMBL2078432 | 1.00 | AXL (0.48) | — | |
| Hydrochloric Acid SCHEMBL31308615 | 0.98 | AXL (0.47) | — | |
| Hydrochloric Acid SCHEMBL311520 | 0.98 | AXL (0.47) | — | |
| SCHEMBL3845938 | 0.98 | AXL (0.47) | — | |
| Hydrochloric Acid SCHEMBL310786 | 0.98 | AXL (0.47) | — | |
| SCHEMBL7500296 | 0.98 | AXL (0.47) | — | |
| SCHEMBL15880172 | 0.92 | AXL (0.42) | — | |
| Methylene Chloride SCHEMBL27892265 | 0.92 | AXL (0.42) | — | |
| Urea SCHEMBL15380856 | 0.90 | RIPK1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568972-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | claimed |
| CN-119654326-A | Novel heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119490449-A | Hydroxamic acid compound containing N-benzyl-2- (5-phenylpyridin-2-yl) acetamide and preparation method and application thereof | 沈阳药科大学 | 2025-02-21 | — | — | CN | claimed |
| CN-115246822-B | Pyrimidine compound, and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-10-29 | — | — | CN | claimed |
| CN-117756810-A | Preparation method of trans-7H-pyrrolo [2,3-d ] pyrimidine compound | 苏州莱安医药化学技术有限公司 | 2024-03-26 | — | — | CN | claimed |
| WO-2024033277-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | claimed |
| CN-112218631-B | Heterocyclic inhibitors of ATR kinase | 德州大学系统董事会 | 2023-12-22 | — | — | CN | claimed |
| CN-115677704-B | Histone deacetylase 6 inhibitor containing 7H-pyrrolo [2,3-d ] pyrimidine structure, and preparation method and application thereof | 山东大学 | 2023-12-05 | — | — | CN | claimed |
| CN-111606929-B | Preparation method of Degatinib | 中瀚(齐河县)生物医药科技有限公司 | 2023-07-07 | — | — | CN | claimed |
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2023-06-01 | — | — | US | claimed |
| WO-2023281149-A1 | TAU-TUBULIN KINASE (TTBK) INHIBITOR COMPOUNDS | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2023-01-12 | — | — | WO | claimed |
| CN-108697714-B | Fused pyrimidine compound or salt thereof | 大鹏药品工业株式会社 | 2022-04-26 | — | — | CN | claimed |
| CN-112279854-B | Preparation method of 7H-pyrrolo [2,3-d ] pyrimidine compound | 常州齐晖药业有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-109134564-B | Lactulose glycoside derivatives, preparation method and application thereof | 合肥锐思生物医药有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-122103147-A | Preparation method of 4-chloropyrrolopyrimidine | — | 2026-05-29 | — | — | CN | disclosed |
| EP-4747250-A1 | KINASE INHIBITORS | The United States Of America, As Represented By The Secretary, Department of Health and Human Services (US) | 2026-05-27 | — | — | EP | disclosed |
| CN-112839649-B | CXCR4 inhibitor compositions and methods of making and using the same | X4 制药有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-110072865-B | Pyrrolo-aromatic heterocyclic compounds, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-114026094-A | PRMT5 inhibitor | 印度鲁宾有限公司 | 2022-02-08 | — | — | CN | disclosed |
| CN-114008025-A | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2022-02-01 | — | — | CN | disclosed |