SCHEMBL64925

SCHEMBL64925

c1ncc2cc[nH]c2n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29407705 1.00
SCHEMBL2078432 1.00 AXL (0.48)
Hydrochloric Acid SCHEMBL31308615 0.98 AXL (0.47)
Hydrochloric Acid SCHEMBL311520 0.98 AXL (0.47)
SCHEMBL3845938 0.98 AXL (0.47)
Hydrochloric Acid SCHEMBL310786 0.98 AXL (0.47)
SCHEMBL7500296 0.98 AXL (0.47)
SCHEMBL15880172 0.92 AXL (0.42)
Methylene Chloride SCHEMBL27892265 0.92 AXL (0.42)
Urea SCHEMBL15380856 0.90 RIPK1 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9104 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3478295-B1 SYNTHESIS OF N-(HETEROARYL)-PYRROLO[3,2-D]PYRIMIDIN-2-AMINES PHARMACOSMOS HOLDING AS (DK) 2026-05-27 EP claimed
US-20250388599-A1 TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS OF USE GENENTECH INC (US) 2025-12-25 US claimed
WO-2025149628-A1 PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE ASTRAZENECA AB (SE) 2025-07-17 WO claimed
EP-4568972-A1 NEW HETEROCYCLIC COMPOUNDS F. Hoffmann-La Roche AG (CH) 2025-06-18 EP claimed
CN-119998357-A Compositions and methods for liquid phase oligonucleotide synthesis 兆维生物科技公司 2025-05-13 CN claimed
US-20250135015-A1 CELL-PENETRATING PEPTIDES FOR ANTISENSE DELIVERY SAREPTA THERAPEUTICS, INC. (US) 2025-05-01 US claimed
WO-2025082069-A1 COMPOUND BINDING TO CRBN PROTEIN AND DEGRADATION AGENT OF PROTEIN 中国海洋大学 2025-04-24 WO claimed
CN-115867560-B Nucleosides and nucleotides having 3' acetal end-capping groups 伊鲁米纳剑桥有限公司 2025-03-28 CN claimed
CN-119639879-A 3' -O-modified nucleotide analogs with different cleavable linkers for linking fluorescent labels to bases for sequencing by DNA synthesis 哥伦比亚大学董事会 2025-03-18 CN claimed
CN-110709089-B 3' -O-modified nucleotide analogs with different cleavable linkers for linking fluorescent labels to bases for sequencing by DNA synthesis 哥伦比亚大学董事会 2024-12-06 CN claimed
WO-1994013668-A1 NOVEL BICYCLIC PYRIMIDINE COMPOUNDS, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS ADIR ET COMPAGNIE (FR) 1994-06-23 WO claimed
EP-0549886-A1 Process for the preparation of pyrrolo[2,3-d]pyrimidines THE TRUSTEES OF PRINCETON UNIVERSITY (US) 1993-07-07 EP claimed
EP-0534323-A1 Process for the preparation of high chloride tabular grain emulsions (II) EASTMAN KODAK COMPANY (US) 1993-03-31 EP claimed
US-5178997-A A fused N-heterocyclic compound as a grain growth modifier; materials handling EASTMAN KODAK COMPANY (US) 1993-01-12 US claimed
EP-0514540-A1 PYRROLO 2,3-d]PYRIMIDINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL PREPARATION COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT TEIJIN LIMITED (JP) 1992-11-25 EP claimed
WO-1992012718-A1 ADENOSINE KINASE INHIBITORS GENSIA, INC. (US) 1992-08-06 WO claimed
EP-0496617-A1 Adenosine kinase inhibitors GENSIA, INC. (US) 1992-07-29 EP claimed
CN-1048705-A Process for preparing pyrrolopyrimidines and intermediates thereof TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1991-01-23 CN claimed
EP-0402903-A1 Production of pyrrolopyrimidines and intermediates therefor Takeda Chemical Industries, Ltd. (JP) 1990-12-19 EP claimed
US-4028184-A CULTURING CORYNEBACTERIUM, ARTHROBACTER, MICROBACTERIUM KIKKOMAN SHOYU CO., LTD. (JA) 1977-06-07 US claimed