Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690535 | 0.88 | HTT (0.45) | MAOBHTTHTR2ARAB9AALDH1A1 | |
| SCHEMBL11042629 | 0.86 | HTR2A (0.46) | MAOBHTTHTR2ARAB9AALDH1A1 | |
| SCHEMBL2945134 | 0.82 | POLB (0.41) | MAOBHTTHTR2ARAB9AALDH1A1 | |
| SCHEMBL11566178 | 0.81 | HTR2A (0.54) | MAOBHTTHTR2ARAB9AALDH1A1 | |
| SCHEMBL10465292 | 0.81 | MAOB (0.56) | MAOBHTTHTR2ARAB9AALDH1A1 | |
| SCHEMBL26658 | 0.80 | ALDH1A1 (0.56) | MAOBHTTRAB9AALDH1A1MAPT | |
| SCHEMBL5445040 | 0.79 | MAOB (0.54) | MAOBHTTHTR2ARAB9AALDH1A1 | |
| SCHEMBL9169044 | 0.78 | ALDH1A1 (0.41) | MAOBHTTHTR2ARAB9AALDH1A1 | |
| SCHEMBL9281133 | 0.78 | ALDH1A1 (0.41) | MAOBHTTHTR2ARAB9AALDH1A1 | |
| SCHEMBL9169055 | 0.78 | ALDH1A1 (0.41) | MAOBHTTHTR2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292436-B | Method for preparing 2-diazo-acetoacetic acid p-nitrobenzyl ester by using microchannel reactor | 蒲鹏 | 2023-04-18 | — | — | CN | claimed |
| CN-114516820-A | Method for preparing 2-diazo-acetoacetic acid p-nitrobenzyl ester | 山东艾孚特科技有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-113292436-A | Method for preparing 2-diazo-acetoacetic acid p-nitrobenzyl ester by using microchannel reactor | 蒲鹏 | 2021-08-24 | — | — | CN | claimed |
| CN-112961156-A | Preparation process of antibiotic drug panipenem | 苏州莱克施德药业有限公司 | 2021-06-15 | — | — | CN | claimed |
| CN-107556212-B | Method for preparing 2-diazo-acetoacetic acid p-nitrobenzyl ester | 台州昌霖化工科技有限公司 | 2020-03-24 | — | — | CN | claimed |
| JP-8027168-A | — | — | None | — | — | JP | disclosed |
| CN-113292436-B | Method for preparing 2-diazo-acetoacetic acid p-nitrobenzyl ester by using microchannel reactor | 蒲鹏 | 2023-04-18 | — | — | CN | disclosed |
| CN-113292436-B | Method for preparing 2-diazo-acetoacetic acid p-nitrobenzyl ester by using microchannel reactor | 蒲鹏 | 2023-04-18 | — | — | CN | disclosed |
| CN-113292436-B | Method for preparing 2-diazo-acetoacetic acid p-nitrobenzyl ester by using microchannel reactor | 蒲鹏 | 2023-04-18 | — | — | CN | disclosed |
| CN-114516820-A | Method for preparing 2-diazo-acetoacetic acid p-nitrobenzyl ester | 山东艾孚特科技有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-114516820-A | Method for preparing 2-diazo-acetoacetic acid p-nitrobenzyl ester | 山东艾孚特科技有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-114516820-A | Method for preparing 2-diazo-acetoacetic acid p-nitrobenzyl ester | 山东艾孚特科技有限公司 | 2022-05-20 | — | — | CN | disclosed |
| EP-0247431-B1 | SUBSTITUTED 6-HYDROXYMETHYLCARBAPENEM ANTIBIOTICS, PROCESS FOR THEIR PREPARATION AND THEIR USE | BAYER AG (DE) | 1990-08-01 | — | — | EP | disclosed |
| EP-0232822-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE FLUORINE-CONTAINING COMPOUNDS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-05-23 | — | — | EP | disclosed |
| US-4863916-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| US-4841042-A | Process for the preparation of carbapenem intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | disclosed |
| EP-0247431-A1 | Substituted 6-hydroxymethylcarbapenem antibiotics, process for their preparation and their use | BAYER AG (DE) | 1987-12-02 | — | — | EP | disclosed |
| EP-0232822-A1 | Process for preparing optically active fluorine-containing compounds | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-08-19 | — | — | EP | disclosed |
| US-4683296-A | ANTIBIOTICS, SILATION | BRISTOL-MYERS COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
| EP-0195963-A1 | Process for the preparation of carbapenem intermediates | BAYER AG (DE) | 1986-10-01 | — | — | EP | disclosed |