Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2940773 | 0.88 | MAOB (0.48) | HTTHTR2ARAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL11042629 | 0.85 | HTR2A (0.46) | HTTHTR2ARAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL8404254 | 0.82 | ALDH1A1 (0.49) | HTTRAB9AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL2945134 | 0.81 | POLB (0.41) | HTTHTR2ARAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL9169055 | 0.80 | ALDH1A1 (0.41) | HTTHTR2ARAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL9281133 | 0.80 | ALDH1A1 (0.41) | HTTHTR2ARAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL9670137 | 0.79 | ALDH1A1 (0.39) | HTTHTR2ARAB9AALDH1A1MAOB | |
| SCHEMBL10493918 | 0.79 | ALDH1A1 (0.37) | HTTHTR2ARAB9AALDH1A1MAPT | |
| SCHEMBL9871979 | 0.78 | TDP1 (0.41) | HTTHTR2ARAB9AALDH1A1IDO1 | |
| SCHEMBL11061401 | 0.78 | TDP1 (0.43) | HTTHTR2ARAB9AALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415365-B | Carbapenem compounds | 幽兰医药有限公司 | 2022-08-09 | — | — | CN | disclosed |
| US-4746736-A | THIENAMYCINS, BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1988-05-24 | — | — | US | disclosed |
| US-4683296-A | ANTIBIOTICS, SILATION | BRISTOL-MYERS COMPANY (US) | 1987-07-28 | — | — | US | disclosed |