Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.43 |
| ▸ | BDKRB2 | P30411 | 7/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.42 |
| ▸ | NMT2 | O60551 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29541526 | 0.91 | ITGB3 (0.40) | CAPN1BDKRB2OPRM1OPRD1F2 | |
| SCHEMBL30099571 | 0.88 | NMUR2 (0.43) | BDKRB2OPRM1OPRD1 | |
| SCHEMBL31146384 | 0.87 | ACE (0.39) | BDKRB2OPRM1F2F10 | |
| SCHEMBL21581703 | 0.85 | CAPN1 (0.45) | CAPN1BDKRB2OPRM1OPRD1F2 | |
| SCHEMBL26454162 | 0.85 | CAPN1 (0.45) | CAPN1BDKRB2OPRM1OPRD1F2 | |
| SCHEMBL29763113 | 0.84 | CAPN1 (0.41) | CAPN1OPRM1OPRD1NMT2NMT1 | |
| SCHEMBL30620966 | 0.84 | XIAP (0.45) | CAPN1OPRM1OPRD1 | |
| SCHEMBL31534097 | 0.81 | BDKRB2 (0.41) | CAPN1BDKRB2OPRM1OPRD1 | |
| SCHEMBL29568037 | 0.81 | CAPN1 (0.42) | CAPN1OPRD1 | |
| SCHEMBL29565363 | 0.81 | OPRM1 (0.43) | BDKRB2OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220175962-A1 | GENE THERAPY COMPOSITIONS AND METHODS FOR TREATING PARKINSON'S DISEASE | SIO GENE THERAPIES INC (US) | 2022-06-09 | — | — | US | disclosed |
| US-11279954-B2 | Catecholamine enzyme fusions | OXFORD BIOMEDICA (UK) LTD. (GB) | 2022-03-22 | — | — | US | disclosed |