SCHEMBL29408396

SCHEMBL29408396

CC#C[C@@H](CC(=O)O)c1ccc(OS(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17669284 1.00 FFAR1 (0.64) FFAR1
SCHEMBL17386238 0.89 FFAR1 (0.53) FFAR1
SCHEMBL17386236 0.89 FFAR1 (0.53) FFAR1
SCHEMBL13616548 0.82 FFAR1 (0.91) FFAR1
SCHEMBL4652352 0.79 CXCR2 (0.57) FFAR1
SCHEMBL22800008 0.79 FFAR1 (0.65) FFAR1
SCHEMBL21121318 0.79 FFAR1 (0.65) FFAR1
SCHEMBL21121317 0.79 FFAR1 (0.65) FFAR1
SCHEMBL30618892 0.78 FFAR1 (1.00) FFAR1
SCHEMBL3520418 0.78 FFAR1 (0.81) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11731961-B2 Phenyl propionic acid derivatives and uses thereof ILDONG PHARMACEUTICAL CO., LTD. (KR) 2023-08-22 US disclosed
EP-3555076-B1 NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF IL DONG PHARMA (KR) 2023-04-05 EP disclosed
US-20220112185-A1 NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF ILDONG PHARMACEUTICAL CO., LTD. (KR) 2022-04-14 US disclosed
US-20220064154-A1 NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF ILDONG PHARMACEUTICAL CO, LTD. (KR) 2022-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220064154-A1 NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF GPR119, GPR65, GPR55 FFAR1 10/4885
US-20220112185-A1 NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF GPR119, GPR55, GPR65 FFAR1 7/4885
US-11731961-B2 Phenyl propionic acid derivatives and uses thereof GPR119, GPR65, GPR55 FFAR1 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.