SCHEMBL29408565

SCHEMBL29408565

COCCO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc21

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA1 P30542 2/20 0.72
▸ ADORA3 P0DMS8 4/20 0.69
▸ PI4KA P42356 2/20 0.69
▸ PI4K2B Q8TCG2 2/20 0.69
▸ PI4K2A Q9BTU6 2/20 0.69
▸ PI4KB Q9UBF8 2/20 0.69
▸ DPP4 P27487 1/20 0.69
▸ MEN1 O00255 1/20 0.69
▸ SLC28A1 O00337 1/20 0.69
▸ MAP3K7 O43318 1/20 0.69
▸ SLC28A2 O43868 1/20 0.69
▸ GAPDH P04406 1/20 0.69
▸ MAPK1 P28482 1/20 0.69
▸ ADORA2A P29274 1/20 0.69
▸ ADORA2B P29275 1/20 0.69
▸ STAT6 P42226 1/20 0.69
▸ KMT2A Q03164 1/20 0.69
▸ SMN1; SMN2 Q16637 1/20 0.69
▸ DOT1L Q8TEK3 1/20 0.69
▸ SLC29A1 Q99808 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28680450 1.00 ADORA1 (0.72) ADORA1ADORA3PI4KAPI4K2BPI4K2A
SCHEMBL1060588 1.00 ADORA1 (0.72) ADORA1ADORA3PI4KAPI4K2BPI4K2A
SCHEMBL26370816 1.00 ADORA1 (0.72) ADORA1ADORA3PI4KAPI4K2BPI4K2A
SCHEMBL1060584 1.00 ADORA1 (0.72) ADORA1ADORA3PI4KAPI4K2BPI4K2A
SCHEMBL21999787 0.92 ADORA1 (0.61) ADORA1ADORA3PI4KAPI4K2BPI4K2A
SCHEMBL25966341 0.92 ADORA1 (0.61) ADORA1ADORA3PI4KAPI4K2BPI4K2A
SCHEMBL31139492 0.92 ADORA3 (0.69) ADORA1ADORA3PI4KAPI4K2BPI4K2A
SCHEMBL5220374 0.92 ADORA3 (0.69) ADORA1ADORA3PI4KAPI4K2BPI4K2A
SCHEMBL5220384 0.92 ADORA3 (0.69) ADORA1ADORA3PI4KAPI4K2BPI4K2A
SCHEMBL29750660 0.91 ADORA1 (0.68) ADORA1ADORA3PI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026097135-A1 RIG-I INHIBITORS Pharmorage Pty Limited (AU) 2026-05-15 — — WO claimed
CN-117321206-A IL-34 antisense agents and methods of use thereof 诺格拉制药有限公司 2023-12-29 — — CN claimed
CN-114729363-A IL-34 antisense agents and methods of use thereof 诺格拉制药有限公司 2022-07-08 — — CN claimed
CN-122095094-A Compositions targeting KLKB1 and methods of use thereof — 2026-05-26 — — CN disclosed
WO-2026097135-A1 RIG-I INHIBITORS Pharmorage Pty Limited (AU) 2026-05-15 — — WO disclosed
WO-2026102260-A1 CRISPR-RELATED METHODS AND COMPOSITIONS TARGETING ANGIOPOIETIN LIKE 3 (ANGPTL3) EDITAS MEDICINE, INC. (US) 2026-05-15 — — WO disclosed
CN-122036831-A Oligonucleotide purification method 上海奥锐特生物科技有限公司 2026-05-15 — — CN disclosed
WO-2026101913-A1 SIRNAS TARGETING COMPLEMENT FACTOR H-RELATED (CFHR) GENE TRANSCRIPTS AND METHODS OF USE ALNYLAM PHARMACEUTICALS, INC. (US) 2026-05-15 — — WO disclosed
EP-4727929-A2 5'-MODIFIED MONOMERS, OLIGONUCLEOTIDES AND DOUBLE-STRANDED RNAS Alnylam Pharmaceuticals, Inc. (US) 2026-04-22 — — EP disclosed
US-20260103714-A1 ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF CANAVAN DISEASE CONTERA PHARMA AS (DK) 2026-04-16 — — US disclosed
EP-3458464-B1 STEREOSELECTIVE SYNTHESIS OF PHOSPHOROTHIOATE OLIGORIBONUCLEOTIDES ETH ZUERICH (CH) 2026-04-15 — — EP disclosed
WO-2022087041-A1 METHODS AND COMPOSITIONS FOR TREATING PRIMARY HYPEROXALURIA ALNYLAM PHARMACEUTICALS, INC. (US) 2022-04-28 — — WO disclosed
EP-3987030-A2 PPM1A INHIBITORS AND METHODS OF USING SAME Quralis Corporation (US) 2022-04-27 — — EP disclosed
CN-114375194-A Treatment of angiopoietin-like 7(ANGPTL7) -related diseases 艾姆皮瑞克公司 2022-04-19 — — CN disclosed
WO-2022072356-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ANGIOPOIETIN LIKE 7 (ANGPTL7) RELATED DISEASES EMPIRICO INC. (US) 2022-04-07 — — WO disclosed
WO-2022056127-A9 IRNA COMPOSITIONS AND METHODS FOR SILENCING GROWTH FACTOR RECEPTOR BOUND PROTEIN 10 (GRB10) OR GROWTH FACTOR RECEPTOR BOUND PROTEIN 14 (GRB14) IN THE LIVER ALNYLAM PHARMACEUTICALS, INC. (US) 2022-04-07 — — WO disclosed
EP-3976059-A2 TREATMENT OF ANGIOPOIETIN LIKE 7 (ANGPTL7) RELATED DISEASES EMPIRICO INC. (US) 2022-04-06 — — EP disclosed
CN-107690480-B Evaluation of CAS9 molecule/guide RNA molecule complexes 爱迪塔斯医药公司 2022-03-22 — — CN disclosed
CN-108368507-B iRNA compositions of programmed cell death 1 ligand 1(PD-L1) and methods of use thereof 阿尔尼拉姆医药品有限公司 2022-03-22 — — CN disclosed
WO-2022056127-A2 IRNA COMPOSITIONS AND METHODS FOR SILENCING GROWTH FACTOR RECEPTOR BOUND PROTEIN 10 (GRB10) OR GROWTH FACTOR RECEPTOR BOUND PROTEIN 14 (GRB14) IN THE LIVER ALNYLAM PHARMACEUTICALS, INC. (US) 2022-03-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103714-A1 ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF CANAVAN DISEASE NAT10, NAT1, NAA40 ADORA1 1286/4885ADORA3 1427/4885PI4KA 2879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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