Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.66 |
| ▸ | PI4KA | P42356 | 2/20 | 0.66 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.66 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.66 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.66 |
| ▸ | DPP4 | P27487 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.66 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.66 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.66 |
| ▸ | GAPDH | P04406 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.66 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.66 |
| ▸ | STAT6 | P42226 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.66 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26370816 | 0.91 | ADORA1 (0.72) | ADORA1ADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL1060588 | 0.91 | ADORA1 (0.72) | ADORA1ADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL29408565 | 0.91 | ADORA1 (0.72) | ADORA1ADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL1060584 | 0.91 | ADORA1 (0.72) | ADORA1ADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL28680450 | 0.91 | ADORA1 (0.72) | ADORA1ADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL843167 | 0.89 | ADORA3 (0.72) | ADORA1ADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL20493425 | 0.89 | ADORA3 (0.72) | ADORA1ADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL30670297 | 0.89 | ADORA3 (0.72) | ADORA1ADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL1019966 | 0.89 | ADORA3 (0.72) | ADORA1ADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL6517630 | 0.87 | ADORA3 (0.69) | ADORA1ADORA3PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262623-A1 | METHOD OF TREATING HBV/HIV COINFECTION | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2025-12-26 | — | — | WO | disclosed |
| WO-2025242771-A1 | NOVEL USE | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) | 2025-11-27 | — | — | WO | disclosed |
| WO-2025242321-A1 | NOVEL USE | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) | 2025-11-27 | — | — | WO | disclosed |
| US-20230340488-A1 | TREATMENT OF SKIN DISEASES AND DISORDERS USING INHIBITORS OF KALLIKREIN-RELATED PEPTIDASES (KLK) | EXICURE OPERATING COMPANY (US) | 2023-10-26 | — | — | US | disclosed |
| EP-4192477-A1 | TREATMENT OF SKIN DISEASES AND DISORDERS USING INHIBITORS OF KALLIKREIN-RELATED PEPTIDASES (KLK) | Exicure Operating Company (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022150369-A1 | COMPOUNDS FOR THE TREATMENT OF BATTEN DISEASE | EXICURE OPERATING COMPANY (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2022147541-A1 | COMPOUNDS FOR MODULATING SCN9A EXPRESSION | EXICURE OPERATING COMPANY (US) | 2022-07-07 | — | — | WO | disclosed |