SCHEMBL1060588

SCHEMBL1060588

COCCO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc21

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA1 P30542 2/20 0.72
▸ ADORA3 P0DMS8 4/20 0.69
▸ PI4KA P42356 2/20 0.69
▸ PI4K2B Q8TCG2 2/20 0.69
▸ PI4K2A Q9BTU6 2/20 0.69
▸ PI4KB Q9UBF8 2/20 0.69
▸ DPP4 P27487 1/20 0.69
▸ MEN1 O00255 1/20 0.69
▸ SLC28A1 O00337 1/20 0.69
▸ MAP3K7 O43318 1/20 0.69
▸ SLC28A2 O43868 1/20 0.69
▸ GAPDH P04406 1/20 0.69
▸ MAPK1 P28482 1/20 0.69
▸ ADORA2A P29274 1/20 0.69
▸ ADORA2B P29275 1/20 0.69
▸ STAT6 P42226 1/20 0.69
▸ KMT2A Q03164 1/20 0.69
▸ SMN1; SMN2 Q16637 1/20 0.69
▸ DOT1L Q8TEK3 1/20 0.69
▸ SLC29A1 Q99808 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28680450 1.00 ADORA1 (0.72) ADORA1ADORA3PI4KAPI4K2BPI4K2A
SCHEMBL26370816 1.00 ADORA1 (0.72) ADORA1ADORA3PI4KAPI4K2BPI4K2A
SCHEMBL29408565 1.00 ADORA1 (0.72) ADORA1ADORA3PI4KAPI4K2BPI4K2A
SCHEMBL1060584 1.00 ADORA1 (0.72) ADORA1ADORA3PI4KAPI4K2BPI4K2A
SCHEMBL21999787 0.92 ADORA1 (0.61) ADORA1ADORA3PI4KAPI4K2BPI4K2A
SCHEMBL25966341 0.92 ADORA1 (0.61) ADORA1ADORA3PI4KAPI4K2BPI4K2A
SCHEMBL31139492 0.92 ADORA3 (0.69) ADORA1ADORA3PI4KAPI4K2BPI4K2A
SCHEMBL5220374 0.92 ADORA3 (0.69) ADORA1ADORA3PI4KAPI4K2BPI4K2A
SCHEMBL5220384 0.92 ADORA3 (0.69) ADORA1ADORA3PI4KAPI4K2BPI4K2A
SCHEMBL29750660 0.91 ADORA1 (0.68) ADORA1ADORA3PI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025201529-A1 COMPOUNDS FOR SYNTHESIZING MODIFIED SMALL ACTIVATING RNA MOLECULES, MODIFIED SMALL ACTIVATING RNA MOLECULES AND USES THEREOF RACTIGEN THERAPEUTICS (CN) 2025-10-02 — — WO claimed
US-12319916-B2 Modulation of gene transcription using antisense oligonucleotides targeting regulatory RNAs CAMP4 THERAPEUTICS CORPORATION (US) 2025-06-03 — — US claimed
US-20240368604-A1 IL-34 ANTISENSE AGENTS AND METHODS OF USING SAME NOGRA PHARMA LTD (IE) 2024-11-07 — — US claimed
US-20240336924-A1 MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION 2024-10-10 — — US claimed
US-12071623-B2 IL-34 antisense agents and methods of using same NOGRA PHARMA LIMITED (IE) 2024-08-27 — — US claimed
EP-4341403-A1 IL-34 ANTISENSE AGENTS AND METHODS OF USING SAME Nogra Pharma Limited (IE) 2024-03-27 — — EP claimed
US-20240093197-A1 IL-34 ANTISENSE AGENTS AND METHODS OF USING SAME NOGRA PHARMA LIMITED (IE) 2024-03-21 — — US claimed
CN-117321206-A IL-34 antisense agents and methods of use thereof 诺格拉制药有限公司 2023-12-29 — — CN claimed
US-20230002770-A1 IL-34 ANTISENSE AGENTS AND METHODS OF USING SAME NOGRA PHARMA LIMITED (IE) 2023-01-05 — — US claimed
WO-2022243299-A1 IL-34 ANTISENSE AGENTS AND METHODS OF USING SAME NOGRA PHARMA LIMITED (IE) 2022-11-24 — — WO claimed
CN-114729363-A IL-34 antisense agents and methods of use thereof 诺格拉制药有限公司 2022-07-08 — — CN claimed
EP-4741411-A2 OLIGONUCLEOTIDE PRODUCTION METHOD, AND NUCLEOSIDE, NUCLEOTIDE, OR OLIGONUCLEOTIDE AJINOMOTO CO., INC. (JP) 2026-05-13 — — EP disclosed
EP-4720294-A2 MODIFIED UNC13A OLIGONUCLEOTIDES Quralis Corporation (US) 2026-04-08 — — EP disclosed
EP-4683644-A1 FULLY MODIFIED MIR-34A AND RELATED CONJUGATES, COMPOSITIONS AND METHODS OF USE Purdue Research Foundation (US) 2026-01-28 — — EP disclosed
WO-2025242321-A1 NOVEL USE GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) 2025-11-27 — — WO disclosed
US-6172209-B1 MOLECULAR HYBRIDIZATION, GENETIC ENGINEERING; NUCLEASE RESISTANCE ISIS PHARMACEUTICALS INC. 2001-01-09 — — US disclosed
WO-2000076554-A1 LIGAND-CONJUGATED OLIGOMERIC COMPOUNDS ISIS PHARMACEUTICALS, INC. (US) 2000-12-21 — — WO disclosed
EP-1019539-A1 COMBINATORIAL ANTISENSE LIBRARY Oasis Biosciences, Inc. (US) 2000-07-19 — — EP disclosed
WO-2000020429-A1 3',5'-CYCLIC PHOSPHATE COMPOUNDS AND METHODS THEREOF ISIS PHARMACEUTICALS, INC. (US) 2000-04-13 — — WO disclosed
WO-1999018238-A1 COMBINATORIAL ANTISENSE LIBRARY OASIS BIOSCIENCES, INC. (US) 1999-04-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240336924-A1 MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CPS1, CTPS1, CTPS2 ADORA1 4273/4885ADORA3 4551/4885PI4KA 3876/4885
US-12319916-B2 Modulation of gene transcription using antisense oligonucleotides targeting regulatory RNAs CPS1, CTPS1, CTPS2 ADORA1 4273/4885ADORA3 4551/4885PI4KA 3876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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