SCHEMBL29408702

SCHEMBL29408702

Cc1cc(C)c(CN2CCc3c(Cl)cc(-c4c(C)noc4C)c(Cl)c3C2=O)c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EZH2 Q15910 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29408704 1.00 EZH2 (1.00) EZH2
SCHEMBL15813960 1.00 EZH2 (1.00) EZH2
SCHEMBL17382971 0.90 EZH2 (1.00) EZH2
SCHEMBL17382900 0.90 EZH2 (0.81) EZH2
SCHEMBL17383009 0.90 EZH2 (0.81) EZH2
SCHEMBL17382696 0.89 EZH2 (0.80) EZH2
SCHEMBL17382684 0.88 EZH2 (0.79) EZH2
SCHEMBL17382695 0.88 EZH2 (0.79) EZH2
SCHEMBL17383003 0.86 EZH2 (0.89) EZH2
SCHEMBL17383311 0.85 EZH2 (0.75) EZH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250311689-A1 SEEDLING GERMINATION AND GROWTH CONDITIONS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2025-10-09 US claimed
US-20250144056-A1 ANTIMICROBIAL HOST DEFENSE PEPTIDE-INDUCING COMPOSITIONS AND METHODS OF PRODUCTION AND USE THEREOF BOARD OF REGENTS FOR THE OKLAHOMA AGRICULTURAL AND MECH COLLEGES (US) 2025-05-08 US claimed
WO-2025059442-A1 MODULATING PLANT RESPONSES TO STRESS AND GROWTH WITH CHEMICALS REMOTE EPIGENETICS INC. (US) 2025-03-20 WO claimed
WO-2025028596-A1 METHOD FOR PRODUCING NATURAL KILLER CELLS 株式会社ヘリオス 2025-02-06 WO claimed
EP-4423254-A1 COMPOSITIONS AND METHODS FOR PROMOTING IN VITRO MATURATION OF CELLS Memorial Sloan Kettering Cancer Center (US) 2024-09-04 EP claimed
US-20240279600-A1 COMPOSITIONS AND METHODS FOR PROMOTING IN VITRO MATURATION OF CELLS MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2024-08-22 US claimed
WO-2023076554-A9 COMPOSITIONS AND METHODS FOR PROMOTING IN VITRO MATURATION OF CELLS MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2024-07-11 WO claimed
WO-2023147573-A2 ANTIMICROBIAL HOST DEFENSE PEPTIDE-INDUCING COMPOSITIONS AND METHODS OF PRODUCTION AND USE THEREOF BOARD OF REGENTS FOR THE OKLAHOMA AGRICULTURAL AND MECHANICAL COLLEGES (US) 2023-08-03 WO claimed
CN-116510024-A Composition, preparation method and application thereof 上海复东生物医药有限责任公司 2023-08-01 CN claimed
US-20230123585-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING CANCER USING DEUBIQUITINASE INHIBITORS UNIV CHICAGO (US) 2023-04-20 US claimed
WO-2023056236-A1 SEEDLING GERMINATION AND GROWTH CONDITIONS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2023-04-06 WO claimed
US-20220280526-A1 AGENT FOR THE TREATMENT OF PSORIASIS EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) 2022-09-08 US claimed
US-20220193056-A1 COMPOSITIONS AND METHODS OF TREATING PIK3CA HELICAL DOMAIN MUTANT CANCERS CASE WESTERN RESERVE UNIVERSITY 2022-06-23 US claimed
US-20220127568-A1 COMPOSITIONS AND METHODS FOR GENERATING HAIR CELLS BY INHIBITING EPIGENETIC TARGETS Frequency Therapeutics, Inc. (US) 2022-04-28 US claimed
WO-2022042527-A1 SMALL-MOLECULE DRUG FOR TREATING DISEASES RELATED TO INNER EAR AND INTESTINAL EPITHELIAL TISSUE INJURIES 北京大学 2022-03-03 WO claimed
CN-114085803-A Establishment of organoid culture systems with regenerative properties 北京大学 2022-02-25 CN claimed
US-20250311689-A1 SEEDLING GERMINATION AND GROWTH CONDITIONS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2025-10-09 US disclosed
US-20250144056-A1 ANTIMICROBIAL HOST DEFENSE PEPTIDE-INDUCING COMPOSITIONS AND METHODS OF PRODUCTION AND USE THEREOF BOARD OF REGENTS FOR THE OKLAHOMA AGRICULTURAL AND MECH COLLEGES (US) 2025-05-08 US disclosed
CN-114126624-A HSP90 binding conjugates and combination therapies thereof 塔弗达治疗有限公司 2022-03-01 CN disclosed
CN-114085803-A Establishment of organoid culture systems with regenerative properties 北京大学 2022-02-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127568-A1 COMPOSITIONS AND METHODS FOR GENERATING HAIR CELLS BY INHIBITING EPIGENETIC TARGETS WNT3A, WNT1, MECP2 EZH2 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.