Embusartan

Embusartan

SCHEMBL29409583

CCCCc1cc(C(=O)OC)cc(=O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1F

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BDKRB1 P46663 3/20 0.41
AGTR1 P30556 3/20 0.39
AGTR2 P50052 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Embusartan SCHEMBL167147 1.00 BDKRB1 (0.41) BDKRB1AGTR1AGTR2
Embusartan SCHEMBL5534640 0.95 BDKRB1 (0.38) BDKRB1AGTR1AGTR2
Embusartan SCHEMBL5537210 0.95 BDKRB1 (0.38) BDKRB1AGTR1AGTR2
SCHEMBL5814612 0.91 AGTR1 (0.43) AGTR1AGTR2
SCHEMBL8013981 0.91 AGTR1 (0.39) AGTR1AGTR2
SCHEMBL8009750 0.91
SCHEMBL8007180 0.90
SCHEMBL8433566 0.90
SCHEMBL9412776 0.90 BDKRB1 (0.43) BDKRB1AGTR1AGTR2
Embusartan SCHEMBL5537214 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117042763-A Treatment of inflammatory diseases 戴麦里克斯生物科学有限公司 2023-11-10 CN claimed
CN-116829545-B Substituted pyrazolylpiperidine carboxylic acids 拜耳公司 2026-05-15 CN disclosed
CN-120136863-A Adrenergic receptor ADRAC2 antagonists 拜耳公司 2025-06-13 CN disclosed
CN-120025328-A Adrenergic receptor ADRAC2 antagonists 拜耳公司 2025-05-23 CN disclosed
CN-120025327-A Adrenergic receptor ADRAC2 antagonists 拜耳公司 2025-05-23 CN disclosed
CN-119816305-A Use of MILVEXIAN in the treatment or prevention of ischemic stroke 百时美施贵宝公司 2025-04-11 CN disclosed
CN-114929694-B Adrenergic receptor ADRAC2 antagonists 拜耳公司 2025-02-07 CN disclosed
CN-119278042-A Chymase inhibitors for selective dissolution of thrombi in thrombotic or thromboembolic disorders 索克普拉健康与人文科学公司 2025-01-07 CN disclosed
CN-115554300-B Diazabicyclo-substituted imidazopyrimidines and their use for the treatment of respiratory disorders 拜耳股份公司 2024-10-29 CN disclosed
CN-117042763-A Treatment of inflammatory diseases 戴麦里克斯生物科学有限公司 2023-11-10 CN disclosed
CN-116063580-A Peptide analogues 艾得佩索拉公司 2023-05-05 CN disclosed
CN-115583959-A Diazabicyclo-substituted imidazopyrimidines and their use for the treatment of respiratory disorders 拜耳股份公司 2023-01-10 CN disclosed
CN-115554300-A Diazabicyclo-substituted imidazopyrimidines and their use for the treatment of respiratory disorders 拜耳股份公司 2023-01-03 CN disclosed
CN-115554299-A Diazabicyclo-substituted imidazopyrimidines and their use for the treatment of respiratory disorders 拜耳股份公司 2023-01-03 CN disclosed
CN-110719911-B Diazabicyclo-substituted imidazopyrimidines and their use for the treatment of respiratory disorders 拜耳股份公司 2022-10-21 CN disclosed
CN-115175681-A Use of sGC activators for the treatment of ophthalmic diseases 拜耳公司 2022-10-11 CN disclosed
CN-114981257-A Substituted pyrazolopiperidinecarboxylic acids 拜耳公司 2022-08-30 CN disclosed
CN-114929694-A Adrenergic receptor ADRAC2 antagonists 拜耳公司 2022-08-19 CN disclosed
CN-108690016-B Pyrazolopyridines and uses thereof 广东东阳光药业有限公司 2022-08-12 CN disclosed
CN-114174326-A Long-term stable adrenomedullin analogues and uses thereof 拜耳公司 2022-03-11 CN disclosed