SCHEMBL29409702

SCHEMBL29409702

CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2sccc2C)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 1.00
KMT2A Q03164 1/20 1.00
PTGER4 P35408 1/20 0.82
PTGER3 P43115 1/20 0.82
AGTR1 P30556 1/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL238048 1.00 MEN1 (1.00) MEN1KMT2APTGER4PTGER3AGTR1
SCHEMBL5213348 0.93 MEN1 (0.88) MEN1KMT2APTGER4PTGER3AGTR1
SCHEMBL3490486 0.93 MEN1 (0.86) MEN1KMT2APTGER4PTGER3AGTR1
Potassium SCHEMBL3490489 0.93 MEN1 (0.86) MEN1KMT2APTGER4PTGER3AGTR1
SCHEMBL3489772 0.90 PTGER4 (1.00) MEN1KMT2APTGER4PTGER3AGTR1
SCHEMBL9565889 0.89 AGTR1 (0.83) AGTR1
L-159913 SCHEMBL9144158 0.88 AGTR1 (1.00) AGTR1
SCHEMBL9565941 0.88 AGTR1 (0.86) PTGER4PTGER3AGTR1
SCHEMBL29433721 0.88 PTGER4 (0.82) MEN1KMT2APTGER4PTGER3AGTR1
SCHEMBL9566072 0.88 PTGER4 (0.82) MEN1KMT2APTGER4PTGER3AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230279353-A1 METHODS TO ENHANCE DELIVERY AND ENGRAFTMENT OF STEM CELLS INCLUDING THE IDENTIFICATION OF SPECIFIC PROSTAGANDIN E2 RECEPTORS UNIV INDIANA RES & TECH CORP (US) 2023-09-07 US claimed
US-11459545-B2 Methods to enhance delivery and engraftment of stem cells including the identification of specific prostaglandin E2 receptors INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2022-10-04 US claimed
US-20250333702-A1 CELLS WITH INCREASED IMMUNO-REGULATORY PROPERTIES AND METHODS FOR THEIR USE AND MANUFACTURE THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-10-30 US disclosed
US-20250101381-A1 CELLS WITH INCREASED IMMUNO-REGULATORY PROPERTIES AND METHODS FOR THEIR USE AND MANUFACTURE THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-03-27 US disclosed
US-20230279353-A1 METHODS TO ENHANCE DELIVERY AND ENGRAFTMENT OF STEM CELLS INCLUDING THE IDENTIFICATION OF SPECIFIC PROSTAGANDIN E2 RECEPTORS UNIV INDIANA RES & TECH CORP (US) 2023-09-07 US disclosed
US-20230002733-A1 CELLS WITH INCREASED IMMUNO-REGULATORY PROPERTIES AND METHODS FOR THEIR USE AND MANUFACTURE THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2023-01-05 US disclosed
US-11459545-B2 Methods to enhance delivery and engraftment of stem cells including the identification of specific prostaglandin E2 receptors INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2022-10-04 US disclosed
US-20220118021-A1 ENHANCED STEM CELL COMPOSITION FATE THERAPEUTICS INC (US) 2022-04-21 US disclosed
US-20220054553-A1 METHODS OF TREATING ISCHEMIA FATE THERAPEUTICS INC (US) 2022-02-24 US disclosed