Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.88 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.82 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.82 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium SCHEMBL3490489 | 0.99 | MEN1 (0.86) | MEN1KMT2APTGER4PTGER3AGTR1 | |
| SCHEMBL3490486 | 0.99 | MEN1 (0.86) | MEN1KMT2APTGER4PTGER3AGTR1 | |
| SCHEMBL238048 | 0.93 | MEN1 (1.00) | MEN1KMT2APTGER4PTGER3AGTR1 | |
| SCHEMBL29409702 | 0.93 | MEN1 (1.00) | MEN1KMT2APTGER4PTGER3AGTR1 | |
| SCHEMBL6056618 | 0.92 | MEN1 (0.75) | MEN1KMT2APTGER4PTGER3AGTR1 | |
| Potassium SCHEMBL6056620 | 0.92 | MEN1 (0.75) | MEN1KMT2APTGER4PTGER3AGTR1 | |
| SCHEMBL3489772 | 0.90 | PTGER4 (1.00) | MEN1KMT2APTGER4PTGER3AGTR1 | |
| SCHEMBL9565990 | 0.90 | AGTR1 (0.84) | PTGER4PTGER3AGTR1 | |
| SCHEMBL9565999 | 0.89 | AGTR1 (0.83) | AGTR1 | |
| SCHEMBL9565941 | 0.88 | AGTR1 (0.86) | PTGER4PTGER3AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450813-B1 | ANTAGONISTS OF PROSTAGLANDIN RECEPTORS EP2 AND/OR EP4 FOR THE TREATMENT OF MENORRHAGIA | MEDICAL RES COUNCIL (GB) | 2007-08-29 | — | — | EP | claimed |
| EP-0526001-A1 | Substituted triazolinones | MERCK & CO. INC. (US) | 1993-02-03 | — | — | EP | claimed |
| EP-0526001-A1 | Substituted triazolinones | MERCK & CO. INC. (US) | 1993-02-03 | — | — | EP | disclosed |