Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.84 |
| ▸ | MAPT | P10636 | 6/20 | 0.84 |
| ▸ | APP | P05067 | 6/20 | 0.84 |
| ▸ | RAB9A | P51151 | 6/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.84 |
| ▸ | INSR | P06213 | 3/20 | 0.84 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.84 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9841114 | 1.00 | MEN1 (0.84) | MEN1KMT2AMAPTAPPRAB9A | |
| SCHEMBL9841113 | 1.00 | MEN1 (0.84) | MEN1KMT2AMAPTAPPRAB9A | |
| SCHEMBL31447671 | 1.00 | MEN1 (0.84) | MEN1KMT2AMAPTAPPRAB9A | |
| SCHEMBL476579 | 0.92 | MEN1 (1.00) | MEN1KMT2AMAPTAPPRAB9A | |
| SCHEMBL29433017 | 0.92 | MEN1 (1.00) | MEN1KMT2AMAPTAPPRAB9A | |
| SCHEMBL29413750 | 0.92 | MEN1 (1.00) | MEN1KMT2AMAPTAPPRAB9A | |
| SCHEMBL476578 | 0.92 | MEN1 (1.00) | MEN1KMT2AMAPTAPPRAB9A | |
| Bromide SCHEMBL8389953 | 0.90 | MEN1 (0.97) | MEN1KMT2AMAPTAPPRAB9A | |
| Bromide SCHEMBL8389954 | 0.90 | MEN1 (0.97) | MEN1KMT2AMAPTAPPRAB9A | |
| Iodide SCHEMBL8390905 | 0.90 | MEN1 (0.97) | MEN1KMT2AMAPTAPPRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250340547-A1 | NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2025-11-06 | — | — | US | disclosed |
| US-12195454-B2 | Compounds for imaging tau proteins that accumulate in the brain | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2025-01-14 | — | — | US | disclosed |
| US-20240083893-A1 | COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2024-03-14 | — | — | US | disclosed |
| US-11667628-B2 | Compounds for imaging tau proteins that accumulate in brain | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2023-06-06 | — | — | US | disclosed |
| US-20220056020-A1 | NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN BRAIN | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2022-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240083893-A1 | COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN | MAPT, FABP7, HTT | MEN1 4010/4885KMT2A 2213/4885MAPT 1/4885 |
| US-12195454-B2 | Compounds for imaging tau proteins that accumulate in the brain | MAPT, FABP7, HTT | MEN1 4010/4885KMT2A 2213/4885MAPT 1/4885 |
| US-11667628-B2 | Compounds for imaging tau proteins that accumulate in brain | MAPT, FABP7, HTT | MEN1 3842/4885KMT2A 2585/4885MAPT 1/4885 |
| US-20220056020-A1 | NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN BRAIN | MAPT, FABP7, HTT | MEN1 4174/4885KMT2A 2340/4885MAPT 1/4885 |
| US-20250340547-A1 | NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN | MAPT, FABP7, HTT | MEN1 4288/4885KMT2A 2880/4885MAPT 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.