Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 7/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8062901 | 1.00 | GAA (0.40) | GAALMNAMTNR1AMTNR1BTLR9 | |
| SCHEMBL18531736 | 0.87 | MTNR1A (0.41) | GAALMNAMTNR1AMTNR1BTLR9 | |
| SCHEMBL15007192 | 0.87 | MTNR1A (0.41) | GAALMNAMTNR1AMTNR1BTLR9 | |
| SCHEMBL19215849 | 0.87 | MTNR1A (0.41) | GAALMNAMTNR1AMTNR1BTLR9 | |
| SCHEMBL15007184 | 0.87 | MTNR1A (0.41) | GAALMNAMTNR1AMTNR1BTLR9 | |
| SCHEMBL1265760 | 0.87 | MTNR1A (0.41) | GAALMNAMTNR1AMTNR1BTLR9 | |
| SCHEMBL14856082 | 0.87 | MTNR1A (0.41) | GAALMNAMTNR1AMTNR1BTLR9 | |
| SCHEMBL25259047 | 0.85 | TLR9 (0.41) | GAALMNAMTNR1AMTNR1BTLR9 | |
| SCHEMBL16645216 | 0.85 | TLR9 (0.41) | GAALMNAMTNR1AMTNR1BTLR9 | |
| SCHEMBL25587333 | 0.83 | CCR2 (0.39) | LMNAPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4208448-A1 | NOVEL COMPOUNDS | NRG Therapeutics LTD (GB) | 2023-07-12 | — | — | EP | disclosed |
| WO-2022049377-A1 | NOVEL COMPOUNDS | NRG THERAPEUTICS LTD (GB) | 2022-03-10 | — | — | WO | disclosed |