Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15007192 | 1.00 | MTNR1A (0.41) | MTNR1AMTNR1BPGRLMNAGAA | |
| SCHEMBL18531736 | 1.00 | MTNR1A (0.41) | MTNR1AMTNR1BPGRLMNAGAA | |
| SCHEMBL15007184 | 1.00 | MTNR1A (0.41) | MTNR1AMTNR1BPGRLMNAGAA | |
| SCHEMBL1265760 | 1.00 | MTNR1A (0.41) | MTNR1AMTNR1BPGRLMNAGAA | |
| SCHEMBL14856082 | 1.00 | MTNR1A (0.41) | MTNR1AMTNR1BPGRLMNAGAA | |
| SCHEMBL29410344 | 0.87 | GAA (0.40) | MTNR1AMTNR1BPGRLMNAGAA | |
| SCHEMBL8062901 | 0.87 | GAA (0.40) | MTNR1AMTNR1BPGRLMNAGAA | |
| SCHEMBL15001004 | 0.83 | TAS1R3 (0.52) | MTNR1AMTNR1BPGRLMNAGAA | |
| SCHEMBL15013829 | 0.82 | LMNA (0.38) | PGRLMNAGAAKDM4EALDH1A1 | |
| SCHEMBL15007155 | 0.82 | LMNA (0.38) | PGRLMNAGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004098-B1 | KINASE INHIBITORS | CHIESI FARM SPA (IT) | 2017-08-09 | — | — | EP | disclosed |