Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 7/20 | 0.61 |
| ▸ | NMBR | P28336 | 1/20 | 0.58 |
| ▸ | GRPR | P30550 | 1/20 | 0.58 |
| ▸ | CCKBR | P32239 | 7/20 | 0.57 |
| ▸ | CCKAR | P32238 | 1/20 | 0.56 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.55 |
| ▸ | IL23R | Q5VWK5 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29533287 | 0.98 | CCKBR (0.60) | GLP1RNMBRGRPRCCKBRCCKAR | |
| SCHEMBL29389186 | 0.92 | IL23R (0.62) | GLP1RCCKBRCCKARC5AR1IL23R | |
| SCHEMBL30037155 | 0.92 | IL23R (0.62) | GLP1RCCKBRCCKARC5AR1IL23R | |
| SCHEMBL29410268 | 0.92 | IL23R (0.62) | GLP1RCCKBRCCKARC5AR1IL23R | |
| SCHEMBL29389409 | 0.90 | IL23R (0.64) | CCKBRCCKARIL23R | |
| SCHEMBL29534029 | 0.90 | IL23R (0.61) | GLP1RCCKBRCCKARC5AR1IL23R | |
| SCHEMBL30037407 | 0.89 | IL23R (0.61) | GLP1RCCKBRCCKARC5AR1IL23R | |
| SCHEMBL29581449 | 0.86 | GLP1R (0.66) | GLP1RIL23R | |
| SCHEMBL29533546 | 0.86 | C5AR1 (0.63) | GLP1RCCKBRC5AR1IL23R | |
| SCHEMBL29702143 | 0.85 | CCKBR (0.74) | GRPRCCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120154608-A | Application of traditional Chinese medicine compound as targeting itch receptor MRGPRX and MRGPRX2 antagonist | 山东大学 | 2025-06-17 | — | — | CN | disclosed |
| WO-2025106999-A1 | DEPRIVATION OF HUMAN PLURIPOTENT STEM CELL-DERIVED TRPV1+, MRGPRX1+ AND SCN9A+ SENSORY NEURONS AND THEIR FUNCTIONAL CHARACTERIZATION | THE JOHNS HOPKINS UNIVERSITY (US) | 2025-05-22 | — | — | WO | disclosed |