Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21045473 | 1.00 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2NPC1MAPTTSHR | |
| SCHEMBL29411490 | 0.88 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2NPC1MAPTTSHR | |
| SCHEMBL21045225 | 0.88 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2NPC1MAPTTSHR | |
| SCHEMBL21045594 | 0.85 | MEN1 (0.48) | ALDH1A1SMN1; SMN2NPC1MAPTHPGD | |
| SCHEMBL29411399 | 0.85 | MEN1 (0.48) | ALDH1A1SMN1; SMN2NPC1MAPTHPGD | |
| SCHEMBL21045396 | 0.85 | HIF1A (0.50) | ALDH1A1SMN1; SMN2NPC1MAPTTSHR | |
| SCHEMBL29411495 | 0.85 | HIF1A (0.50) | ALDH1A1SMN1; SMN2NPC1MAPTTSHR | |
| SCHEMBL29411365 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2NPC1MAPTTSHR | |
| SCHEMBL21045194 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2NPC1MAPTTSHR | |
| SCHEMBL21045242 | 0.79 | EPHX2 (0.70) | SMN1; SMN2NPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250188035-A1 | TUBULIN INHIBITORS | LIN BIOSCIENCE LLC (US) | 2025-06-12 | — | — | US | disclosed |
| US-12247010-B2 | Tubulin inhibitors | LIN BIOSCIENCE INC. (TW) | 2025-03-11 | — | — | US | disclosed |
| US-20220089539-A1 | TUBULIN INHIBITORS | LIN BIOSCIENCE INC. (TW) | 2022-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089539-A1 | TUBULIN INHIBITORS | TUBB3, TUBB1, TUBB | ALDH1A1 3048/4885SMN1; SMN2 1062/4885NPC1 421/4885 |
| US-12247010-B2 | Tubulin inhibitors | TUBB3, TUBB1, TUBB | ALDH1A1 3048/4885SMN1; SMN2 1062/4885NPC1 421/4885 |
| US-20250188035-A1 | TUBULIN INHIBITORS | TUBB3, TUBB1, TUBB | ALDH1A1 3048/4885SMN1; SMN2 1062/4885NPC1 421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.