Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21045203 | 1.00 | SMN1; SMN2 (0.63) | SMN1; SMN2MEN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL29411624 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2MEN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL21045090 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2MEN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL21045240 | 0.79 | MAPT (0.67) | SMN1; SMN2MEN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL29411387 | 0.79 | MAPT (0.67) | SMN1; SMN2MEN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL169905 | 0.78 | ALDH1A1 (1.00) | SMN1; SMN2MEN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL29729259 | 0.78 | ALDH1A1 (1.00) | SMN1; SMN2MEN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL21235027 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL30920079 | 0.77 | TSHR (0.77) | SMN1; SMN2MEN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL21227017 | 0.77 | TSHR (0.77) | SMN1; SMN2MEN1ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250188035-A1 | TUBULIN INHIBITORS | LIN BIOSCIENCE LLC (US) | 2025-06-12 | — | — | US | disclosed |
| US-12247010-B2 | Tubulin inhibitors | LIN BIOSCIENCE INC. (TW) | 2025-03-11 | — | — | US | disclosed |
| US-20220089539-A1 | TUBULIN INHIBITORS | LIN BIOSCIENCE INC. (TW) | 2022-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089539-A1 | TUBULIN INHIBITORS | TUBB3, TUBB1, TUBB | SMN1; SMN2 1062/4885MEN1 955/4885ALDH1A1 3048/4885 |
| US-12247010-B2 | Tubulin inhibitors | TUBB3, TUBB1, TUBB | SMN1; SMN2 1062/4885MEN1 955/4885ALDH1A1 3048/4885 |
| US-20250188035-A1 | TUBULIN INHIBITORS | TUBB3, TUBB1, TUBB | SMN1; SMN2 1062/4885MEN1 955/4885ALDH1A1 3048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.