Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | PDE6D | O43924 | 1/20 | 0.66 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.66 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | CTSD | P07339 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | TNF | P01375 | 1/20 | 0.59 |
| ▸ | BRD4 | O60885 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KCNK13 | Q9HB14 | 1/20 | 0.57 |
| ▸ | GUSB | P08236 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230485 | 1.00 | ALDH1A1 (0.66) | ALDH1A1PDE6DALDH2ALDH3A1KDM4E | |
| SCHEMBL29412135 | 0.87 | L3MBTL1 (0.70) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL28486406 | 0.87 | L3MBTL1 (0.70) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL7179121 | 0.87 | ALDH1A1 (0.68) | ALDH1A1PDE6DALDH2ALDH3A1KDM4E | |
| Hydrochloric Acid SCHEMBL7177527 | 0.87 | ALDH1A1 (0.68) | ALDH1A1PDE6DALDH2ALDH3A1KDM4E | |
| Hydrochloric Acid SCHEMBL7185166 | 0.87 | ALDH1A1 (0.68) | ALDH1A1PDE6DALDH2ALDH3A1KDM4E | |
| Hydrochloric Acid SCHEMBL7171218 | 0.87 | ALDH1A1 (0.68) | ALDH1A1PDE6DALDH2ALDH3A1KDM4E | |
| Hydrochloric Acid SCHEMBL7175827 | 0.87 | ALDH1A1 (0.68) | ALDH1A1PDE6DALDH2ALDH3A1KDM4E | |
| Hydrochloric Acid SCHEMBL7177021 | 0.87 | ALDH1A1 (0.68) | ALDH1A1PDE6DALDH2ALDH3A1KDM4E | |
| SCHEMBL7807909 | 0.86 | KMT2A (0.62) | ALDH1A1PDE6DALDH2ALDH3A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057930-A1 | BENZIMIDAZOLE COMPOUND HAVING ENDOTHELIAL LIPASE INHIBITION EFFECT, AND APPLICATION | 盐城师范学院 | 2022-03-24 | — | — | WO | disclosed |