Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | CTSD | P07339 | 5/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GUSB | P08236 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29412135 | 1.00 | L3MBTL1 (0.70) | L3MBTL1CTSDCYP19A1KDM4EALDH1A1 | |
| SCHEMBL230485 | 0.87 | ALDH1A1 (0.66) | L3MBTL1CTSDKDM4EALDH1A1HPGD | |
| SCHEMBL29411979 | 0.87 | ALDH1A1 (0.66) | L3MBTL1CTSDKDM4EALDH1A1HPGD | |
| SCHEMBL2610093 | 0.84 | L3MBTL1 (0.71) | L3MBTL1CTSDKDM4EALDH1A1HPGD | |
| SCHEMBL13351524 | 0.81 | ALDH1A1 (0.66) | L3MBTL1CTSDKDM4EALDH1A1HPGD | |
| SCHEMBL10005369 | 0.81 | L3MBTL1 (0.63) | L3MBTL1CTSDKDM4EALDH1A1HPGD | |
| SCHEMBL15314762 | 0.80 | ALDH1A1 (0.73) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29411911 | 0.80 | ALDH1A1 (0.73) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29411929 | 0.78 | ALDH1A1 (0.61) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28381278 | 0.78 | CTSD (0.60) | L3MBTL1CTSDKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978301-B | Benzimidazole compound with endothelial lipase inhibition effect and application thereof | 盐城师范学院 | 2022-08-02 | — | — | CN | disclosed |
| CN-111978301-A | Benzimidazole compound with endothelial lipase inhibition effect and application thereof | 盐城师范学院 | 2020-11-24 | — | — | CN | disclosed |