SCHEMBL30008333

SCHEMBL30008333

CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(C)=O)[C@@H](C)CC)[C@@H](C)CC)C(C)C

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ PTH1R Q03431 9/20 0.66
▸ GRPR P30550 1/20 0.65
▸ CXCR4 P61073 2/20 0.64
▸ RXFP1 Q9HBX9 1/20 0.64
▸ GLP1R P43220 5/20 0.64
▸ NR3C1 P04150 2/20 0.62
▸ ECE1 P42892 1/20 0.62
▸ MUS81 Q96NY9 1/20 0.62
▸ CCKBR P32239 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30946722 0.97 PTH1R (0.66) PTH1RGRPRCXCR4RXFP1GLP1R
SCHEMBL29412274 0.91 GLP1R (0.73) PTH1RGRPRRXFP1GLP1RNR3C1
SCHEMBL29774757 0.91 GRPR (0.66) PTH1RGRPRCXCR4RXFP1GLP1R
SCHEMBL30408986 0.90 PTH1R (0.67) PTH1RGRPRCXCR4RXFP1GLP1R
SCHEMBL31140800 0.90 GLP1R (0.70) PTH1RRXFP1GLP1RNR3C1ECE1
SCHEMBL29736864 0.90 NR3C1 (0.72) GLP1RNR3C1ECE1MUS81CCKBR
SCHEMBL29491080 0.89 NR3C1 (0.76) GLP1RNR3C1ECE1MUS81CCKBR
SCHEMBL29736869 0.87 NR3C1 (0.72) GRPRGLP1RNR3C1ECE1MUS81
SCHEMBL30744286 0.87 NR3C1 (0.71) PTH1RGRPRRXFP1GLP1RNR3C1
SCHEMBL30744278 0.87 GRPR (0.69) PTH1RGRPRCXCR4RXFP1GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4633680-A1 THYCLOTIDE PEPTIDE CONJUGATES WITH CELL PERMEABILITY AND INHIBITORY ACTIVITY The United States of America, as represented by the Secretary, Department of Health and Human Services (US) 2025-10-22 — — EP disclosed
CN-113286820-B Methods and compounds for targeting sortilin receptors and inhibiting angiogenesis mimicry 特拉斯福特普拉斯公司 2025-04-08 — — CN disclosed
CN-118772291-A Acidic surface-assisted dissolution short peptide tag for improving recombinant protein expression efficiency 宜明(济南)生物科技有限公司 2024-10-15 — — CN disclosed
US-20240226128-A1 NOVEL COMPOUNDS WITH DUAL INHIBITION ACTIVITY AGAINST SARS-COV-2 CRITICAL ENZYMES RDRP, MPRO AND HUMAN TMPRSS2 UNIVERSITY OF SHARJAH (AE) 2024-07-11 — — US disclosed
CN-116496365-B Acidic surface-assisted dissolution short peptide tag for improving recombinant protein expression efficiency 宜明(济南)生物科技有限公司 2024-06-25 — — CN disclosed
WO-2024129497-A1 THYCLOTIDE PEPTIDE CONJUGATES WITH CELL PERMEABILITY AND INHIBITORY ACTIVITY THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2024-06-20 — — WO disclosed
WO-2024119434-A1 SOLUBILIZATION-ASSISTING SHORT PEPTIDE TAG WITH ACIDIC SURFACE FOR IMPROVING EXPRESSION EFFICIENCY OF RECOMBINANT PROTEIN 宜明(济南)生物科技有限公司 2024-06-13 — — WO disclosed
US-11786537-B2 Therapeutic inhibition affinity of copper (II) complex and their diazenyl pyridinone heterocyclic ligands against SARS-CoV2 KING ABDULAZIZ UNIVERSITY (SA) 2023-10-17 — — US disclosed
US-20230255981-A1 THERAPEUTIC INHIBITION AFFINITY OF COPPER (II) COMPLEX AND THEIR DIAZENYL PYRIDINONE HETEROCYCLIC LIGANDS AGAINST SARS-COV2 KING ABDULAZIZ UNIVERSITY (SA) 2023-08-17 — — US disclosed
US-11723932-B2 Microorganisms programmed to produce immune modulators and anti-cancer therapeutics in tumor cells SYNLOGIC OPERATING COMPANY, INC. (US) 2023-08-15 — — US disclosed
CN-107629129-B Method for producing and purifying polypeptides 清华大学 2023-08-04 — — CN disclosed
CN-116496365-A Acidic surface-assisted dissolution short peptide tag for improving recombinant protein expression efficiency 济南宜明医疗科技有限公司 2023-07-28 — — CN disclosed
US-20230226122-A1 MICROORGANISMS PROGRAMMED TO PRODUCE IMMUNE MODULATORS AND ANTI-CANCER THERAPEUTICS IN TUMOR CELLS SYNLOGIC OPERATING COMPANY, INC. 2023-07-20 — — US disclosed
US-20230131339-A1 EPI-X4 BASED PEPTIDES AND DERIVATIVES THEREOF BADEN-WUERTTEMBERG STIFTUNG GGMBH (DE) 2023-04-27 — — US disclosed
US-11608331-B2 Anti-SARS CoV-2 inhibitors by dual viral-host targeting UNIVERSITY OF SHARJAH (AE) 2023-03-21 — — US disclosed
EP-4110790-A2 EPI-X4 BASED PEPTIDES AND DERIVATIVES THEREOF Universität Ulm (DE) 2023-01-04 — — EP disclosed
US-20220402905-A1 Anti-SARS CoV-2 inhibitors by dual viral-host targeting UNIVERSITY OF SHARJAH (AE) 2022-12-22 — — US disclosed
WO-2022254388-A1 DISCOVERY OF ANTI-SARS-COV-2 INHIBITORS BY DUAL VIRAL-HOST TARGETING UNIVERSITY OF SHARJAH (AE) 2022-12-08 — — WO disclosed
US-11471494-B2 Microorganisms programmed to produce immune modulators and anti-cancer therapeutics in tumor cells SYNLOGIC OPERATING COMPANY, INC. (US) 2022-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402905-A1 Anti-SARS CoV-2 inhibitors by dual viral-host targeting ACE2, TMPRSS2, ACE PTH1R 4671/4885GRPR 3093/4885CXCR4 572/4885
US-11723932-B2 Microorganisms programmed to produce immune modulators and anti-cancer therapeutics in tumor cells PDCD1, CD274, PDCD4 PTH1R 2798/4885GRPR 1839/4885CXCR4 3326/4885
US-11608331-B2 Anti-SARS CoV-2 inhibitors by dual viral-host targeting ACE2, TMPRSS2, ACE PTH1R 4671/4885GRPR 3093/4885CXCR4 572/4885
US-20230255981-A1 THERAPEUTIC INHIBITION AFFINITY OF COPPER (II) COMPLEX AND THEIR DIAZENYL PYRIDINONE HETEROCYCLIC LIGANDS AGAINST SARS-COV2 ACE2, C1QBP, ACE PTH1R 3106/4885GRPR 4370/4885CXCR4 2531/4885
US-20240226128-A1 NOVEL COMPOUNDS WITH DUAL INHIBITION ACTIVITY AGAINST SARS-COV-2 CRITICAL ENZYMES RDRP, MPRO AND HUMAN TMPRSS2 TMPRSS2, ACE2, TMPRSS4 PTH1R 3528/4885GRPR 2531/4885CXCR4 3507/4885
US-11786537-B2 Therapeutic inhibition affinity of copper (II) complex and their diazenyl pyridinone heterocyclic ligands against SARS-CoV2 ACE2, C1QBP, ACE PTH1R 3106/4885GRPR 4370/4885CXCR4 2531/4885
US-20230131339-A1 EPI-X4 BASED PEPTIDES AND DERIVATIVES THEREOF CXCR4, SDF4, ACKR3 PTH1R 1615/4885GRPR 1553/4885CXCR4 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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