Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 12/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29412850 | 1.00 | DHODH (0.49) | DHODHHDAC6LMNAGAAMEN1 | |
| SCHEMBL25342511 | 1.00 | DHODH (0.49) | DHODHHDAC6LMNAGAAMEN1 | |
| SCHEMBL29412868 | 0.84 | KIT (0.46) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL25342226 | 0.84 | KIT (0.46) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL29412915 | 0.83 | MAPT (0.43) | LMNAGAAMEN1KMT2AHTT | |
| SCHEMBL25345557 | 0.83 | MAPT (0.43) | LMNAGAAMEN1KMT2AHTT | |
| SCHEMBL25342600 | 0.82 | DHODH (0.59) | DHODHLMNAGAAMEN1KMT2A | |
| SCHEMBL29412847 | 0.82 | DHODH (0.59) | DHODHLMNAGAAMEN1KMT2A | |
| SCHEMBL25343849 | 0.78 | POLR1A (0.53) | — | |
| SCHEMBL29412873 | 0.78 | POLR1A (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022060799-A1 | COMPOUNDS WHICH INHIBIT RNA POLYMERASE AND THEIR USE | THE JOHNS HOPKINS UNIVERSITY (US) | 2022-03-24 | — | — | WO | disclosed |