SCHEMBL29414477

SCHEMBL29414477

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nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 3/20 0.44
MME P08473 5/20 0.41
PTGS1 P23219 1/20 0.38
GSTK1 Q9Y2Q3 1/20 0.38
NMT2 O60551 2/20 0.36
NMT1 P30419 2/20 0.36
QRFPR Q96P65 2/20 0.35
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.35
OPRM1 P35372 1/20 0.34
OPRD1 P41143 1/20 0.34
TERT O14746 1/20 0.34
GLO1 Q04760 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29866316 1.00 TGFBR1 (0.44) TGFBR1MMEPTGS1GSTK1NMT2
SCHEMBL29541562 1.00 TGFBR1 (0.44) TGFBR1MMEPTGS1GSTK1NMT2
SCHEMBL29714329 0.97 TGFBR1 (0.42) TGFBR1MMEPTGS1GSTK1NMT2
SCHEMBL29530629 0.97 TGFBR1 (0.42) TGFBR1MMEPTGS1GSTK1NMT2
SCHEMBL29397392 0.97 TGFBR1 (0.42) TGFBR1MMEPTGS1GSTK1NMT2
SCHEMBL29372719 0.97 TGFBR1 (0.42) TGFBR1MMEPTGS1GSTK1NMT2
SCHEMBL30674928 0.97 TGFBR1 (0.42) TGFBR1MMEPTGS1GSTK1NMT2
SCHEMBL29475227 0.97 TGFBR1 (0.42) TGFBR1MMEPTGS1GSTK1NMT2
SCHEMBL29597633 0.97 TGFBR1 (0.42) TGFBR1MMEPTGS1GSTK1NMT2
SCHEMBL29938092 0.95 TGFBR1 (0.43) TGFBR1MMEPTGS1GSTK1NMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705321-A2 SPYCATCHER ANALOGS AND USES THEREOF Bio-Rad ABD Serotec GmbH (DE) 2026-03-11 EP claimed
US-20250228958-A1 TSP1 INHIBITOR DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-07-17 US claimed
US-12209139-B2 N- and C-terminal tandem tag system for purification KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2025-01-28 US claimed
EP-4467561-A1 TSP1 INHIBITOR Daiichi Sankyo Company, Limited (JP) 2024-11-27 EP claimed
WO-2024231728-A2 SPYCATCHER ANALOGS AND USES THEREOF BIO-RAD ABD SEROTEC GMBH (DE) 2024-11-14 WO claimed
US-20240368234-A1 SPYCATCHER ANALOGS AND USES THEREOF BIO-RAD ABD SEROTEC GMBH (DE) 2024-11-07 US claimed
WO-2023136342-A1 TSP1 INHIBITOR 第一三共株式会社 2023-07-20 WO claimed
WO-2026107236-A1 COMPOSITIONS AND METHODS FOR VACCINATION AGAINST MYCOBACTERIUM TUBERCULOSIS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2026-05-21 WO disclosed
EP-4736889-A2 COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS TO CELLS Yale University (US) 2026-05-06 EP disclosed
EP-4731658-A1 TRANSFERRIN RECEPTOR-BINDING MOLECULES, CONJUGATES THEREOF AND THEIR USES TO PREVENT OR TREAT NERVOUS SYSTEM DISEASES Vect-Horus (FR) 2026-04-29 EP disclosed
EP-4731643-A2 COMPOSITIONS AND METHODS FOR REDUCING PAIN AND INFLAMMATION THROUGH EPIGENETIC MODULATION Navega Therapeutics, Inc. (US) 2026-04-29 EP disclosed
EP-4731657-A2 TRANSFERRIN RECEPTOR-BINDING MOLECULES, CONJUGATES THEREOF AND THEIR USES TO PREVENT OR TREAT MUSCULAR DISEASES Vect-Horus (FR) 2026-04-29 EP disclosed
EP-4713352-A1 CHIMERIC ANTIGEN RECEPTOR COMPOSITIONS, CAR-MAST CELLS FORMED THEREFROM, AND METHODS OF USE THEREOF Yale University (US) 2026-03-25 EP disclosed
WO-2022092828-A1 VACCINE COMPOSITION FOR PREVENTION OR TREATMENT OF SARS-CORONAVIRUS-2 INFECTION 에스케이바이오사이언스 주식회사 2022-05-05 WO disclosed
WO-2022065889-A1 VACCINE COMPOSITION COMPRISING RECOMBINANT PROTEIN FOR PREVENTION OR TREATMENT OF SARS-CORONA VIRUS-2 INFECTION 에스케이바이오사이언스 주식회사 2022-03-31 WO disclosed
EP-3971211-A1 HIDE1 COMPOSITIONS AND METHODS Compugen Ltd. (IL) 2022-03-23 EP disclosed
WO-2022056398-A1 COMPOSITIONS AND METHODS OF USE THEREOF FOR PREVENTION AND TREATMENT OF INFLUENZA INFECTIONS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2022-03-17 WO disclosed
US-20220072160-A1 COMPOSITIONS AND METHODS FOR PROMOTING HOMOLOGY DIRECTED REPAIR EDITAS MEDICINE, INC. 2022-03-10 US disclosed
WO-2022047424-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS TO CELLS YALE UNIVERSITY (US) 2022-03-03 WO disclosed
EP-3941485-A1 ANTIGEN BINDING PROTEINS Bio-Rad ABD Serotec GmbH (DE) 2022-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220072160-A1 COMPOSITIONS AND METHODS FOR PROMOTING HOMOLOGY DIRECTED REPAIR MRE11, DCLRE1A, RAD51 TGFBR1 3999/4885MME 3174/4885PTGS1 4166/4885
US-20250228958-A1 TSP1 INHIBITOR ANXA11, SERPINC1, NPR1 TGFBR1 128/4885MME 2456/4885PTGS1 1185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.