SCHEMBL6158363

SCHEMBL6158363

Cc1ccc(C(NCCCC[C@@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MDM2 Q00987 6/20 0.57
▸ MDM4 O15151 2/20 0.49
▸ TP53 P04637 2/20 0.49
▸ TLR2 O60603 2/20 0.46
▸ KMT2A Q03164 1/20 0.45
▸ TGM2 P21980 1/20 0.44
▸ CASP3 P42574 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL436024 1.00 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL29547181 1.00 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL2288397 1.00 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL29792115 1.00 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL31681399 1.00 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL29362301 1.00 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL21192401 0.97 MDM2 (0.58) MDM2MDM4TP53TLR2KMT2A
SCHEMBL5967470 0.97 MDM2 (0.58) MDM2MDM4TP53TLR2KMT2A
SCHEMBL29401280 0.97 MDM2 (0.58) MDM2MDM4TP53TLR2KMT2A
SCHEMBL31614333 0.94 MDM2 (0.53) MDM2MDM4TP53TLR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110054664-B Side chain fatty acid modified antibacterial peptide analogue containing D-type amino acid and synthesis and application thereof 倪京满 2023-05-26 — — CN claimed
CN-118812662-A Method for preparing ganirelix acetate 杭州昊肽生物科技有限公司 2024-10-22 — — CN disclosed
EP-3027228-B1 MODULAR IMAGING AGENTS CONTAINING AMINO ACIDS AND PEPTIDES ROCHESTER INSTITUTE TECH (US) 2024-10-02 — — EP disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
US-20240209034-A1 ENGINEERING PEPTIDES FOR A A VB6 INTEGRIN BINDING AND RELATED METHODS OF USE AND SYNTHESIS UNIV WASHINGTON (US) 2024-06-27 — — US disclosed
WO-2024081824-A2 SYNTHETIC INTERMEDIATES FOR UNIVERSAL CHIMERIC ANTIGEN RECEPTOR IMMUNE CELL THERAPIES UNIVERSITY OF WASHINGTON (US) 2024-04-18 — — WO disclosed
CN-114401749-B Radionuclide marker and application thereof 北京拓界生物医药科技有限公司 2024-04-16 — — CN disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 — — CN disclosed
US-11674136-B2 DNA-templated macrocycle library PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-06-13 — — US disclosed
CN-110054664-B Side chain fatty acid modified antibacterial peptide analogue containing D-type amino acid and synthesis and application thereof 倪京满 2023-05-26 — — CN disclosed
WO-2022221144-A9 ENGINEERED PEPTIDES FOR ΑVΒ6 INTEGRIN BINDING AND RELATED METHODS OF USE AND SYNTHESIS UNIVERSITY OF WASHINGTON (US) 2023-05-19 — — WO disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
WO-2022221144-A1 ENGINEERED PEPTIDES FOR ΑVΒ6 INTEGRIN BINDING AND RELATED METHODS OF USE AND SYNTHESIS UNIVERSITY OF WASHINGTON (US) 2022-10-20 — — WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
CN-114401749-A Radionuclide marker and application thereof 北京拓界生物医药科技有限公司 2022-04-26 — — CN disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed
EP-1504094-A2 PEPTIDE COMPOUNDS AND THEIR USE AS PROTEASE SUBSTRATES Pharmacia Corporation (US) 2005-02-09 — — EP disclosed
US-20040018561-A1 Peptide compounds and their use as protease substrates PHARMACIA CORPORATION 2004-01-29 — — US disclosed
WO-2003095475-A2 PEPTIDE COMPOUNDS AND THEIR USE AS PROTEASE SUBSTRATES PHARMACIA CORPORATION (US) 2003-11-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11674136-B2 DNA-templated macrocycle library IDE, IAPP, POLRMT MDM2 938/4885MDM4 1827/4885TP53 130/4885
US-20040018561-A1 Peptide compounds and their use as protease substrates MMP3, MMP25, MMP11 MDM2 1389/4885MDM4 1345/4885TP53 478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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