SCHEMBL436024

SCHEMBL436024

Cc1ccc(C(NCCCC[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MDM2 Q00987 6/20 0.57
▸ MDM4 O15151 2/20 0.49
▸ TP53 P04637 2/20 0.49
▸ TLR2 O60603 2/20 0.46
▸ KMT2A Q03164 1/20 0.45
▸ TGM2 P21980 1/20 0.44
▸ CASP3 P42574 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6158363 1.00 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL29547181 1.00 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL2288397 1.00 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL29792115 1.00 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL31681399 1.00 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL29362301 1.00 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL21192401 0.97 MDM2 (0.58) MDM2MDM4TP53TLR2KMT2A
SCHEMBL5967470 0.97 MDM2 (0.58) MDM2MDM4TP53TLR2KMT2A
SCHEMBL29401280 0.97 MDM2 (0.58) MDM2MDM4TP53TLR2KMT2A
SCHEMBL31614333 0.94 MDM2 (0.53) MDM2MDM4TP53TLR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3355931-B1 PROTEIN CONJUGATES NOVO NORDISK AS (DK) 2024-06-26 — — EP disclosed
CN-106139158-B Growth hormone with prolonged in vivo efficacy 诺沃—诺迪斯克保健股份有限公司 2024-06-21 — — CN disclosed
US-20240174622-A1 COMPOUND AND RADIOACTIVE LABELING COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2024-05-30 — — US disclosed
EP-4303213-A1 COMPOUND AND RADIOACTIVE LABELING COMPOUND Nihon Medi-Physics Co., Ltd. (JP) 2024-01-10 — — EP disclosed
CN-117377759-A Self-purified nucleic acid-encoded libraries 约尔格·谢尔曼 2024-01-09 — — CN disclosed
US-20230210110-A1 METHOD FOR INDUCING ENVIRONMENTAL STRESS TOLERANCE IN PLANTS AJINOMOTO CO., INC. (JP) 2023-07-06 — — US disclosed
US-20230210110-A1 METHOD FOR INDUCING ENVIRONMENTAL STRESS TOLERANCE IN PLANTS AJINOMOTO CO., INC. (JP) 2023-07-06 — — US disclosed
CN-116390938-A Exendin-4 analogues TXP制药股份有限公司 2023-07-04 — — CN disclosed
US-20230112418-A1 COMPOUND AND RADIOACTIVE LABELING COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2023-04-13 — — US disclosed
EP-4116306-A1 COMPOUND AND RADIOACTIVE LABELING COMPOUND Nihon Medi-Physics Co., Ltd (JP) 2023-01-11 — — EP disclosed
EP-2323694-A1 CONJUGATED PROTEINS WITH PROLONGED IN VIVO EFFICACY Novo Nordisk Health Care AG (CH) 2011-05-25 — — EP disclosed
WO-2011015649-A1 GROWTH HORMONES WITH PROLONGED IN-VIVO EFFICACY NOVO NORDISK HEALTH CARE AG (CH) 2011-02-10 — — WO disclosed
US-20100197607-A1 MUCIN HYPERSECRETION INHIBITORS AND METHODS OF USE WILLIAMS, MASON L. 2010-08-05 — — US disclosed
WO-2010015668-A1 CONJUGATED PROTEINS WITH PROLONGED IN VIVO EFFICACY NOVO NORDISK A/S (DK) 2010-02-11 — — WO disclosed
US-20090275520-A1 MUCIN HYPERSECRETION INHIBITORS AND METHODS OF USE WILLIAMS, MASON L. 2009-11-05 — — US disclosed
US-7524926-B2 Mucin hypersecretion inhibitors and methods of use BIOMARCK PHARMACEUTICALS, LTD. (US) 2009-04-28 — — US disclosed
EP-1858538-A2 MUCIN HYPERSECRETION INHIBITORS BASED ON THE STRUCTURE OF MANS AND METHODS OF USE Biomarck Pharmaceuticals, Ltd. (US) 2007-11-28 — — EP disclosed
US-20060205664-A1 Mucin hypersecretion inhibitors and methods of use WILLIAMS, MASON L. 2006-09-14 — — US disclosed
WO-2006078899-A2 MUCIN HYPERSECRETION INHIBITORS BASED ON THE STRUCTURE OF MANS AND METHODS OF USE BIOMARCK PHARMACEUTICALS, LTD. (US) 2006-07-27 — — WO disclosed
EP-0989136-A1 PEPTIDES HAVING CYCLIC STRUCTURES AND EXERTING P53 PROTEIN ACTIVTY-RESTORING EFFECT ON P53 PROTEIN MUTANTS KYOWA HAKKO KOGYO CO., LTD. (JP) 2000-03-29 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210110-A1 METHOD FOR INDUCING ENVIRONMENTAL STRESS TOLERANCE IN PLANTS DAO, ALAD, BCAT1 MDM2 2670/4885MDM4 3845/4885TP53 4035/4885
US-20230112418-A1 COMPOUND AND RADIOACTIVE LABELING COMPOUND ALB, TFRC, FABP2 MDM2 717/4885MDM4 1173/4885TP53 209/4885
US-20240174622-A1 COMPOUND AND RADIOACTIVE LABELING COMPOUND PSMA2, PSMA1, PSMA3 MDM2 191/4885MDM4 386/4885TP53 1163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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