Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.43 |
| ▸ | LOX | P28300 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196649 | 0.82 | HSP90AA1 (0.46) | BRAFKDRMAPK14TNNI3KMAP4K4 | |
| SCHEMBL6691249 | 0.80 | KDR (0.49) | RAB9AHTTLTA4HL3MBTL1BRAF | |
| SCHEMBL1895117 | 0.80 | MEN1 (0.50) | SMN1; SMN2NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL29415420 | 0.80 | MEN1 (0.51) | ALDH1A1HTTL3MBTL1BRAFKDR | |
| SCHEMBL169685 | 0.80 | MEN1 (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1HTT | |
| SCHEMBL4929333 | 0.78 | KDR (0.71) | BRAFKDRMAPK14TNNI3K | |
| SCHEMBL12261855 | 0.76 | KDR (0.39) | BRAFKDRMAPK14TNNI3K | |
| SCHEMBL10033144 | 0.76 | RAB9A (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1HTT | |
| SCHEMBL29610302 | 0.76 | LOXL2 (0.52) | SMN1; SMN2NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL147539 | 0.76 | LOXL2 (0.52) | SMN1; SMN2NPC1RAB9ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647685-B2 | Anti-inflammatory 6-phenoxypyrimidine derivatives, process for their preparation and pharmaceutical composition containing them | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-05-12 | — | — | US | claimed |
| US-20180370922-A1 | ANTI-INFLAMMATORY 6-PHENOXYPYRIMIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2018-12-27 | — | — | US | claimed |
| US-20050124498-A1 | Halobenzyl substituted phenylaceto esters and amides and use thereof for prevention of harmful organisms | BAYER CROPSCIENCE AG (DE) | 2005-06-09 | — | — | US | claimed |
| EP-1483248-A1 | HALOBENZYL SUBSTITUTED PHENYLACETO ESTERS AND AMIDES AND USE THEREOF FOR PREVENTION OF HARMFUL ORGANISMS | Bayer CropScience Aktiengesellschaft (DE) | 2004-12-08 | — | — | EP | claimed |
| WO-2003074496-A1 | HALOBENZYL SUBSTITUTED PHENYLACETO ESTERS AND AMIDES AND USE THEREOF FOR PREVENTION OF HARMFUL ORGANISMS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-09-12 | — | — | WO | claimed |
| WO-2025073792-A1 | WRN INHIBITORY COMPOUNDS | FORX THERAPEUTICS AG (CH) | 2025-04-10 | — | — | WO | disclosed |
| US-20250049791-A1 | Synthesis of MEK7 Inhibitors and methods of Use Thereof | NORTHWESTERN UNIVERSITY | 2025-02-13 | — | — | US | disclosed |
| US-20250049791-A1 | Synthesis of MEK7 Inhibitors and methods of Use Thereof | NORTHWESTERN UNIVERSITY | 2025-02-13 | — | — | US | disclosed |
| US-10647685-B2 | Anti-inflammatory 6-phenoxypyrimidine derivatives, process for their preparation and pharmaceutical composition containing them | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-05-12 | — | — | US | disclosed |
| US-10647685-B2 | Anti-inflammatory 6-phenoxypyrimidine derivatives, process for their preparation and pharmaceutical composition containing them | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-05-12 | — | — | US | disclosed |
| US-10647685-B2 | Anti-inflammatory 6-phenoxypyrimidine derivatives, process for their preparation and pharmaceutical composition containing them | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-05-12 | — | — | US | disclosed |
| US-20180370922-A1 | ANTI-INFLAMMATORY 6-PHENOXYPYRIMIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2018-12-27 | — | — | US | disclosed |
| US-6200997-B1 | CYCLIZATION TO GIVE OXAZOLIDINEDIONES AND TRIAZOLIDINEDIONES | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-13 | — | — | US | disclosed |
| EP-0873307-B1 | CYANIMINO OXIME ETHERS, PROCESS AND INTERMEDIATES FOR THE PREPARATION AND USE THEREOF FOR THE CONTROL OF NOXIOUS FUNGI AND ANIMAL PESTS | BASF AG (DE) | 2000-05-31 | — | — | EP | disclosed |
| US-6063813-A | FUNGICIDES AND INSECTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-16 | — | — | US | disclosed |
| US-6043282-A | FUNGICIDES, PESTICIDES, INSECTICIDES, NEMATOCIDES, MITICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-28 | — | — | US | disclosed |
| CN-1161687-A | Phenylacetic acid alkyl esters | BASF AG (DE) | 1997-10-08 | — | — | CN | disclosed |
| US-4427437-A | PLANT GROWTH REGULATORS | ICI AUSTRALIA LIMITED (AU) | 1984-01-24 | — | — | US | disclosed |
| EP-0001187-B1 | 2-PHENOXY-PYRIMIDINES AND THEIR USE AS PESTICIDES | ICI AUSTRALIA LIMITED (AU) | 1983-12-07 | — | — | EP | disclosed |
| EP-0001187-A1 | 2-phenoxy-pyrimidines and their use as pesticides | ICI AUSTRALIA LIMITED (AU) | 1979-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250049791-A1 | Synthesis of MEK7 Inhibitors and methods of Use Thereof | MAPK7, MAP3K7, NRAS | SMN1; SMN2 3147/4885NPC1 3279/4885RAB9A 1983/4885 |
| US-20050124498-A1 | Halobenzyl substituted phenylaceto esters and amides and use thereof for prevention of harmful organisms | HDHD5, GNPAT, PGLS | SMN1; SMN2 4729/4885NPC1 1646/4885RAB9A 2707/4885 |
| US-10647685-B2 | Anti-inflammatory 6-phenoxypyrimidine derivatives, process for their preparation and pharmaceutical composition containing them | IL6, PTGS1, NOS1 | SMN1; SMN2 4347/4885NPC1 3542/4885RAB9A 4107/4885 |
| US-20180370922-A1 | ANTI-INFLAMMATORY 6-PHENOXYPYRIMIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | IL6, PTGS1, NOS1 | SMN1; SMN2 4347/4885NPC1 3542/4885RAB9A 4107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.