Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.63 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.63 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.63 |
| ▸ | APLNR | P35414 | 1/20 | 0.60 |
| ▸ | CALCR | P30988 | 4/20 | 0.53 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.53 |
| ▸ | REN | P00797 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 4/20 | 0.51 |
| ▸ | NTSR2 | O95665 | 3/20 | 0.51 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.51 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30272472 | 0.91 | APLNR (0.57) | MAPK8MAPK9MAPK10APLNRCALCR | |
| SCHEMBL30429121 | 0.90 | MAPK8 (0.65) | MAPK8MAPK9MAPK10APLNRCALCR | |
| SCHEMBL30455824 | 0.89 | MAPK8 (0.57) | MAPK8MAPK9MAPK10APLNRCALCR | |
| SCHEMBL30692723 | 0.88 | APLNR (0.58) | MAPK8MAPK9MAPK10APLNRREN | |
| SCHEMBL38662088 | 0.88 | APLNR (0.63) | MAPK8MAPK9MAPK10APLNRCALCR | |
| SCHEMBL31182889 | 0.87 | MAPK8 (0.68) | MAPK8MAPK9MAPK10APLNRCALCR | |
| SCHEMBL31691539 | 0.87 | APLNR (0.61) | MAPK8MAPK9MAPK10APLNRCALCR | |
| SCHEMBL29359023 | 0.87 | AGTR2 (0.66) | APLNRCALCRF2NTSR2NTSR1 | |
| SCHEMBL31544391 | 0.87 | AGTR1 (0.62) | APLNRCALCRF2NTSR2NTSR1 | |
| SCHEMBL31281747 | 0.86 | MAPK8 (0.60) | MAPK8MAPK9MAPK10APLNRCALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110381984-B | Compositions and methods for improving sexual function | 尼莫克斯股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| EP-4275688-A2 | METHOD OF AMELIORATING OR PREVENTING THE WORSENING OR THE PROGRESSION OF SYMPTOMS OF BPH | Nymox Corporation (BS) | 2023-11-15 | — | — | EP | disclosed |
| CN-116785403-A | Neurofilament peptides for preventing or slowing the progression of prostate cancer | 尼莫克斯股份有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-109310732-B | Neurofilament peptides for preventing or slowing the progression of prostate cancer | 尼莫克斯股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-114099636-A | Method of treating a condition requiring cell destruction or removal using peptides derived from neurofilament proteins | 尼莫克斯制药公司 | 2022-03-01 | — | — | CN | disclosed |