SCHEMBL30284875

SCHEMBL30284875

O=c1c2ccccc2oc2ccc(Br)cc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.67
KDM4E B2RXH2 1/20 0.67
ALDH1A1 P00352 1/20 0.67
GLA P06280 1/20 0.67
CYP3A4 P08684 1/20 0.67
MAPT P10636 1/20 0.67
HPGD P15428 1/20 0.67
PGAM1 P18669 1/20 0.67
CASP1 P29466 1/20 0.67
CASP7 P55210 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
HSD17B10 Q99714 1/20 0.67
TTR P02766 2/20 0.58
NPC1 O15118 4/20 0.57
RAB9A P51151 3/20 0.57
POLB P06746 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
GABRP O00591 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2592127 1.00 MAOA (0.67) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL2588529 0.90 PIM1 (0.58) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL29416622 0.90 PIM1 (0.58) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL31397562 0.89 MAOA (0.67) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL490127 0.89 MAOA (0.67) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL47040 0.87 PIM1 (0.51) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL30593469 0.87 PIM1 (0.51) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL29655725 0.86 MAOA (0.58) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL29655739 0.86 MAOA (0.58) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL28113736 0.86 MAOA (0.58) MAOAKDM4EALDH1A1GLACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115779157-B Reactive biomedical coating and preparation method thereof 国科温州研究院(温州生物材料与工程研究所) 2024-08-16 CN claimed
CN-115779157-A Reactive biomedical coating and preparation method thereof 国科温州研究院(温州生物材料与工程研究所) 2023-03-14 CN claimed
EP-4426679-A1 SPIRO-(INDANE-FLUORENE) TYPE COMPOUNDS AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2024-09-11 EP disclosed
CN-115779157-B Reactive biomedical coating and preparation method thereof 国科温州研究院(温州生物材料与工程研究所) 2024-08-16 CN disclosed
WO-2023078824-A1 SPIRO-(INDANE-FLUORENE) TYPE COMPOUNDS AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2023-05-11 WO disclosed
CN-115779157-A Reactive biomedical coating and preparation method thereof 国科温州研究院(温州生物材料与工程研究所) 2023-03-14 CN disclosed