Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 11/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28978825 | 1.00 | MAT2A (0.45) | MAT2AMAPK8MAPK9MAPK10ALDH1A1 | |
| SCHEMBL28978822 | 0.91 | KDM4E (0.42) | MAT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL29417550 | 0.91 | KDM4E (0.42) | MAT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL29417546 | 0.89 | MAT2A (0.39) | MAT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL28978791 | 0.89 | MAT2A (0.39) | MAT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL28978817 | 0.89 | LMNA (0.43) | MAT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL28874822 | 0.86 | MAT2A (0.59) | MAT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL30038981 | 0.86 | MAT2A (0.59) | MAT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL29417557 | 0.86 | MAT2A (0.42) | MAT2AMAPK8MAPK9MAPK10ALDH1A1 | |
| SCHEMBL28978832 | 0.86 | MAT2A (0.42) | MAT2AMAPK8MAPK9MAPK10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022053022-A1 | METHIONINE ADENOSYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 赛诺哈勃药业（成都）有限公司 | 2022-03-17 | — | — | WO | disclosed |