SCHEMBL2941823

SCHEMBL2941823

Cc1cc(C)c([Si](O)(c2c(C)cc(C)cc2C)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 2/20 0.44
LMNA P02545 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
RAPGEF4 Q8WZA2 3/20 0.39
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SELL P14151 1/20 0.35
SELP P16109 1/20 0.35
SELE P16581 1/20 0.35
ACHE P22303 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34
MMP13 P45452 1/20 0.34
NOS3 P29474 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1686721 0.82 ALDH1A1 (0.44) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL1686911 0.82 ALDH1A1 (0.44) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL10987239 0.79 CYP1A2 (0.38) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL13295957 0.73 RAPGEF4 (0.41) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL13296036 0.73 RAPGEF4 (0.41) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL1314789 0.71 RAPGEF4 (0.39) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL4464617 0.71 RAPGEF4 (0.39) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL16707370 0.71 RAPGEF4 (0.39) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL297423 0.71 RAPGEF4 (0.39) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL20815388 0.69 RAPGEF4 (0.38) ALDH1A1KDM4ELMNAGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7799497-B2 Silanol containing overcoated photoconductors XEROX CORPORATION (US) 2010-09-21 US claimed
US-7781132-B2 Silanol containing charge transport overcoated photoconductors XEROX CORPORATION (US) 2010-08-24 US claimed
US-7670733-B2 Silanol containing photoconductors XEROX CORPORATION (US) 2010-03-02 US claimed
US-20080268356-A1 Silanol containing photoconductors XEROX CORPORATION. 2008-10-30 US claimed
US-20080107985-A1 Silanol containing overcoated photoconductors XEROX CORPORATION 2008-05-08 US claimed
US-20080107979-A1 Silanol containing charge transport overcoated photoconductors XEROX CORPORATION 2008-05-08 US claimed
US-20080057425-A1 Silanol containing perylene photoconductors XEROX CORPORATION 2008-03-06 US claimed
US-20080057423-A1 Titanyl phthalocyanine silanol terphenyl photoconductors XEROX CORPORATION 2008-03-06 US claimed
US-20080057421-A1 Silanol containing perylene photoconductors XEROX CORPORATION 2008-03-06 US claimed
US-20080057422-A1 Titanyl phthalocyanine silanol photoconductors XEROX CORPORATION 2008-03-06 US claimed
US-20080032218-A1 Silanol containing photoconductor XEROX CORPORATION 2008-02-07 US claimed
US-20080020312-A1 Imaging member having antistatic anticurl back coating XEROX CORPORATION (US) 2008-01-24 US claimed
US-20080014516-A1 Silanol containing photoconductors XEROX CORPORATION 2008-01-17 US claimed
US-20080014517-A1 Silanol containing photoconductors XEROX CORPORATION. 2008-01-17 US claimed
US-7846629-B2 Imaging member XEROX CORPORATION (US) 2010-12-07 US disclosed
US-7799497-B2 Silanol containing overcoated photoconductors XEROX CORPORATION (US) 2010-09-21 US disclosed
US-7785756-B2 Overcoated photoconductors with thiophosphate containing charge transport layers XEROX CORPORATION (US) 2010-08-31 US disclosed
US-20080020312-A1 Imaging member having antistatic anticurl back coating XEROX CORPORATION (US) 2008-01-24 US disclosed
US-20080014516-A1 Silanol containing photoconductors XEROX CORPORATION 2008-01-17 US disclosed
US-20080014517-A1 Silanol containing photoconductors XEROX CORPORATION. 2008-01-17 US disclosed