SCHEMBL29418795

SCHEMBL29418795

O=C(NCc1cccc(C(F)(F)F)c1)[C@@H]1C[C@H]2CC[C@@H]1C2

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 4/20 0.67
▸ P2RX7 Q99572 1/20 0.53
▸ KMT2A Q03164 3/20 0.50
▸ TSHR P16473 1/20 0.50
▸ KDM4E B2RXH2 1/20 0.49
▸ MLYCD O95822 1/20 0.49
▸ MEN1 O00255 2/20 0.48
▸ PLA2G1B P04054 2/20 0.48
▸ CYP1A2 P05177 1/20 0.48
▸ CYP3A4 P08684 1/20 0.48
▸ GAA P10253 1/20 0.48
▸ CYP2D6 P10635 1/20 0.48
▸ CYP2C19 P33261 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.48
▸ ATG4B Q9Y4P1 1/20 0.48
▸ POLB P06746 1/20 0.48
▸ LMNA P02545 2/20 0.48
▸ HTT P42858 1/20 0.47
▸ HRH3 Q9Y5N1 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21541951 1.00 HPGD (0.67) HPGDP2RX7KMT2ATSHRKDM4E
SCHEMBL20477558 1.00 HPGD (0.67) HPGDP2RX7KMT2ATSHRKDM4E
SCHEMBL29418612 1.00 HPGD (0.67) HPGDP2RX7KMT2ATSHRKDM4E
SCHEMBL20477540 0.83 HPGD (0.63) HPGDPOLBSCN9A
SCHEMBL29418710 0.83 HPGD (0.63) HPGDPOLBSCN9A
SCHEMBL20477566 0.83 HPGD (0.63) HPGDPOLBSCN9A
SCHEMBL29418763 0.83 HPGD (0.63) HPGDPOLBSCN9A
Bimokalner SCHEMBL22017037 0.81 HPGD (0.67) HPGDKMT2AKDM4EMEN1POLB
Bimokalner SCHEMBL20477551 0.81 HPGD (0.67) HPGDKMT2AKDM4EMEN1POLB
Bimokalner SCHEMBL20477545 0.81 HPGD (0.67) HPGDKMT2AKDM4EMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4247332-B1 NON-AQUEOUS GEL COMPOSITION ACOUSIA THERAPEUTICS GMBH (DE) 2026-04-22 — — EP claimed
US-20260083669-A1 AQUEOUS GEL COMPOSITION ACOUSIA THERAPEUTICS GMBH (DE) 2026-03-26 — — US claimed
CN-117881393-A Aqueous gel composition 阿库西亚医疗有限责任公司 2024-04-12 — — CN claimed
CN-116600787-A Nonaqueous gel composition 阿库西亚医疗有限责任公司 2023-08-15 — — CN claimed
CN-110312710-B Compounds useful as potassium channel openers 阿库西亚医疗有限责任公司 2022-02-15 — — CN claimed
US-20260083669-A1 AQUEOUS GEL COMPOSITION ACOUSIA THERAPEUTICS GMBH (DE) 2026-03-26 — — US disclosed
CN-114105942-B Compounds useful as potassium channel openers 阿库西亚医疗有限责任公司 2024-07-12 — — CN disclosed
EP-4362916-A1 AQUEOUS GEL COMPOSITION Acousia Therapeutics GmbH (DE) 2024-05-08 — — EP disclosed
CN-117881393-A Aqueous gel composition 阿库西亚医疗有限责任公司 2024-04-12 — — CN disclosed
WO-2023222795-A1 AQUEOUS GEL COMPOSITION ACOUSIA THERAPEUTICS GMBH (DE) 2023-11-23 — — WO disclosed
CN-116600787-A Nonaqueous gel composition 阿库西亚医疗有限责任公司 2023-08-15 — — CN disclosed
CN-110312710-B Compounds useful as potassium channel openers 阿库西亚医疗有限责任公司 2022-02-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083669-A1 AQUEOUS GEL COMPOSITION CFTR, AQP3, SLC26A4 HPGD 1470/4885P2RX7 559/4885KMT2A 4703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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