Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CFD | P00746 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20477540 | 1.00 | HPGD (0.63) | HPGDSCN9AMAPK14EPHX2ROCK2 | |
| SCHEMBL20477566 | 1.00 | HPGD (0.63) | HPGDSCN9AMAPK14EPHX2ROCK2 | |
| SCHEMBL29418763 | 1.00 | HPGD (0.63) | HPGDSCN9AMAPK14EPHX2ROCK2 | |
| SCHEMBL20477558 | 0.83 | HPGD (0.67) | HPGDSCN9APOLB | |
| SCHEMBL29418612 | 0.83 | HPGD (0.67) | HPGDSCN9APOLB | |
| SCHEMBL21541951 | 0.83 | HPGD (0.67) | HPGDSCN9APOLB | |
| SCHEMBL29418795 | 0.83 | HPGD (0.67) | HPGDSCN9APOLB | |
| Bimokalner SCHEMBL20477545 | 0.79 | HPGD (0.67) | HPGDPOLBHSD17B10 | |
| Bimokalner SCHEMBL20477551 | 0.79 | HPGD (0.67) | HPGDPOLBHSD17B10 | |
| Bimokalner SCHEMBL22017037 | 0.79 | HPGD (0.67) | HPGDPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247332-B1 | NON-AQUEOUS GEL COMPOSITION | ACOUSIA THERAPEUTICS GMBH (DE) | 2026-04-22 | — | — | EP | claimed |
| US-20260083669-A1 | AQUEOUS GEL COMPOSITION | ACOUSIA THERAPEUTICS GMBH (DE) | 2026-03-26 | — | — | US | claimed |
| EP-4362916-A1 | AQUEOUS GEL COMPOSITION | Acousia Therapeutics GmbH (DE) | 2024-05-08 | — | — | EP | claimed |
| CN-117881393-A | Aqueous gel composition | 阿库西亚医疗有限责任公司 | 2024-04-12 | — | — | CN | claimed |
| US-20240009149-A1 | NON-AQUEOUS GEL COMPOSITION | ACOUSIA THERAPEUTICS GMBH (DE) | 2024-01-11 | — | — | US | claimed |
| WO-2023222795-A1 | AQUEOUS GEL COMPOSITION | ACOUSIA THERAPEUTICS GMBH (DE) | 2023-11-23 | — | — | WO | claimed |
| CN-116600787-A | Nonaqueous gel composition | 阿库西亚医疗有限责任公司 | 2023-08-15 | — | — | CN | claimed |
| CN-110312710-B | Compounds useful as potassium channel openers | 阿库西亚医疗有限责任公司 | 2022-02-15 | — | — | CN | claimed |
| US-20260083669-A1 | AQUEOUS GEL COMPOSITION | ACOUSIA THERAPEUTICS GMBH (DE) | 2026-03-26 | — | — | US | disclosed |
| CN-114105942-B | Compounds useful as potassium channel openers | 阿库西亚医疗有限责任公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-117881393-A | Aqueous gel composition | 阿库西亚医疗有限责任公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-116600787-A | Nonaqueous gel composition | 阿库西亚医疗有限责任公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-110312710-B | Compounds useful as potassium channel openers | 阿库西亚医疗有限责任公司 | 2022-02-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260083669-A1 | AQUEOUS GEL COMPOSITION | CFTR, AQP3, SLC26A4 | HPGD 1470/4885SCN9A 631/4885MAPK14 4265/4885 |
| US-20240009149-A1 | NON-AQUEOUS GEL COMPOSITION | LIPA, MGLL, TAS2R42 | HPGD 3737/4885SCN9A 826/4885MAPK14 2608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.