⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL22091385 | 0.75 | — | — | |
| SCHEMBL7072333 | 0.72 | — | — | |
| Guanidine SCHEMBL165720 | 0.72 | NOS2 (0.42) | — | |
| Guanidine SCHEMBL11330173 | 0.72 | — | — | |
| Guanidine SCHEMBL2003 | 0.72 | — | — | |
| Guanidine SCHEMBL29983942 | 0.72 | — | — | |
| Guanidine SCHEMBL5613752 | 0.72 | — | — | |
| SCHEMBL7415616 | 0.71 | — | — | |
| Guanidine SCHEMBL9322662 | 0.71 | — | — | |
| Guanidine SCHEMBL9790128 | 0.71 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11197933-B2 | Polysubunit opioid prodrugs resistant to overdose and abuse | ELYSIUM THERAPEUTICS, INC. (US) | 2021-12-14 | — | — | US | claimed |
| CN-110023315-B | Novel compound or pharmacologically acceptable salt thereof | 国立研究开发法人理化学研究所 | 2021-11-12 | — | — | CN | claimed |
| US-11129825-B2 | Polysubunit opioid prodrugs resistant to overdose and abuse | ELYSIUM THERAPEUTICS, INC. (US) | 2021-09-28 | — | — | US | claimed |
| EP-3480198-B1 | NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | RIKEN (JP) | 2021-05-05 | — | — | EP | claimed |
| US-20200101166-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2020-04-02 | — | — | US | claimed |
| WO-2018170465-A1 | POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. (US) | 2018-09-20 | — | — | WO | claimed |
| US-7700605-B2 | 2-cyano-pyrimidines and-triazines as cysteine protease inhibitors | NOVARTIS AG (CH) | 2010-04-20 | — | — | US | claimed |
| US-20090291921-A1 | INTEGRASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2009-11-26 | — | — | US | claimed |
| WO-2009067541-A2 | INTEGRASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2009-05-28 | — | — | WO | claimed |
| US-20080214548-A1 | 2-Cyano-Pyrimidines and-Triazines as Cysteine Protease Inhibitors | FLOHR STEFANIE | 2008-09-04 | — | — | US | claimed |
| WO-2007009715-A1 | 2-CYANO-PYRIMIDINES AND -TRIAZINES AS CYSTEINE PROTEASE INHIBITORS | NOVARTIS AG (CH) | 2007-01-25 | — | — | WO | claimed |
| CN-1294117-C | Amidino compounds and salts thereof useful as nitric oxide synthase inhibitors | PHARMACIA CORP (US) | 2007-01-10 | — | — | CN | claimed |
| CN-1419539-A | Amidino compound and salts thereof useful as nitric oxide synahase inhibitors | PHARMACIA CORP (US) | 2003-05-21 | — | — | CN | claimed |
| EP-0842180-B1 | PENAM SULFONES AS BETA-LACTAMASE INHIBITORS | NAEJA PHARMACEUTICAL INC (CA) | 2003-01-22 | — | — | EP | claimed |
| EP-0842180-A1 | NOVEL PENAM SULFONES AS BETA-LACTAMASE INHIBITORS | SYNPHAR LABORATORIES INC. (CA) | 1998-05-20 | — | — | EP | claimed |
| US-5686441-A | 3-(SUBSTITUTED)-3-METHYL-4-THIA-1-AZABICYCLO(3.2.0)HEPTANE-2 -CARBOXYLATE-4,4-DIOXIDES | SYPHAR LABORATORIES, INC. (CA) | 1997-11-11 | — | — | US | claimed |
| WO-1997006172-A1 | NOVEL PENAM SULFONES AS BETA-LACTAMASE INHIBITORS | SYNPHAR LABORATORIES, INC. (US) | 1997-02-20 | — | — | WO | claimed |
| US-5512596-A | Aromatic compounds | GILEAD SCIENCES, INC. (US) | 1996-04-30 | — | — | US | claimed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | claimed |
| US-4150145-A | ANTIBIOTIC, BACTERICIDES | MERCK & CO., INC. (US) | 1979-04-17 | — | — | US | claimed |