Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL659657 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL7856777 | 0.77 | ALDH1A1 (0.38) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL3215328 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAL3MBTL1GSK3B | |
| SCHEMBL5435458 | 0.74 | ALDH1A1 (0.38) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL830474 | 0.74 | CES2 (0.45) | ALDH1A1MAPTLMNAL3MBTL1GSK3B | |
| SCHEMBL11743114 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL27480528 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL7423422 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MAPTLMNAL3MBTL1GSK3B | |
| SCHEMBL28642593 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MAPTL3MBTL1POLBATM | |
| SCHEMBL29136467 | 0.72 | SRD5A2 (0.40) | ALDH1A1MAPTLMNAL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212301-A1 | AN IMPROVED PROCESS FOR PREPARATION OF LETROZOLE AND ITS INTERMEDIATES | Fresenius Kabi Oncology Limited (IN) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009069140-A1 | AN IMPROVED PROCESS FOR PREPARATION OF LETROZOLE AND ITS INTERMEDIATES | DABUR PHARMA LIMITED (IN) | 2009-06-04 | — | — | WO | disclosed |