SCHEMBL29421985

SCHEMBL29421985

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nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 8/20 0.42
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
GRIN3A Q8TCU5 1/20 0.41
PTPN1 P18031 3/20 0.40
CTSD P07339 1/20 0.40
BACE1 P56817 1/20 0.40
BMP1 P13497 1/20 0.40
YWHAZ P63104 2/20 0.39
EGFR P00533 1/20 0.39
TASP1 Q9H6P5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30170575 0.95 OPRM1 (0.40) KEAP1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL29485672 0.90 FOLH1 (0.48) KEAP1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL29422024 0.89 BACE1 (0.51) PTPN1CTSDBACE1YWHAZEGFR
SCHEMBL30170446 0.89 EGFR (0.44) KEAP1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL30170535 0.88 OPRM1 (0.42) KEAP1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL29485686 0.88 GRIN2D (0.46) KEAP1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL30170441 0.86 GLO1 (0.44) KEAP1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL30170524 0.86 GLO1 (0.44) KEAP1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL29485627 0.85 FOLH1 (0.48) KEAP1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL30884000 0.85 MME (0.43) PTPN1CTSDBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12428446-B2 Peptide compound or pharmaceutically acceptable salt thereof EYEBIO KOREA (KR) 2025-09-30 US disclosed
EP-4483959-A2 NOVEL PEPTIDE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF EYEBIO KOREA (KR) 2025-01-01 EP disclosed
EP-3974441-B1 PEPTIDE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF EYEBIO KOREA (KR) 2024-12-04 EP disclosed
US-20240352071-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof EYEBIO KOREA (KR) 2024-10-24 US disclosed
US-20240228538-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof EYEBIO KOREA (KR) 2024-07-11 US disclosed
EP-3974441-A1 NOVEL PEPTIDE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF EYEBIO KOREA (KR) 2022-03-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12428446-B2 Peptide compound or pharmaceutically acceptable salt thereof VIP, FURIN, IAPP KEAP1 2728/4885GRIN2D 3926/4885GRIN3B 1910/4885
US-20240228538-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof VIP, NPPA, NGLY1 KEAP1 3089/4885GRIN2D 3904/4885GRIN3B 2137/4885
US-20240352071-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof VIP, NPPA, NGLY1 KEAP1 3089/4885GRIN2D 3904/4885GRIN3B 2137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.