Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSPO | P30536 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14902271 | 1.00 | KDM4E (0.48) | KDM4EATML3MBTL1TSPOMAPT | |
| SCHEMBL21414463 | 0.95 | KDM4E (0.44) | KDM4EATML3MBTL1TSPOMAPT | |
| SCHEMBL356742 | 0.92 | ALDH1A1 (0.44) | KDM4EL3MBTL1MAPTHTTDNM1 | |
| SCHEMBL28567829 | 0.90 | KDM4E (0.48) | KDM4EATML3MBTL1TSPOMAPT | |
| SCHEMBL29842645 | 0.90 | L3MBTL1 (0.55) | KDM4EATML3MBTL1TSPOMAPT | |
| SCHEMBL782608 | 0.90 | L3MBTL1 (0.55) | KDM4EATML3MBTL1TSPOMAPT | |
| SCHEMBL2721451 | 0.88 | ALDH1A1 (0.41) | KDM4EL3MBTL1MAPTDNM1POLB | |
| SCHEMBL12037390 | 0.88 | KDM4E (0.43) | KDM4EATML3MBTL1TSPOMAPT | |
| SCHEMBL30040723 | 0.87 | L3MBTL1 (0.52) | KDM4EATML3MBTL1TSPOMAPT | |
| SCHEMBL14913074 | 0.87 | L3MBTL1 (0.52) | KDM4EATML3MBTL1TSPOMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112694433-B | Organic small molecule hole transport material and preparation method and application thereof | 华南理工大学 | 2022-12-16 | — | — | CN | disclosed |
| CN-114031609-A | Compound containing carbazole and quinazoline structure and application thereof | 北京燕化集联光电技术有限公司 | 2022-02-11 | — | — | CN | disclosed |