Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.56 |
| ▸ | CDC25B | P30305 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CDC25A | P30304 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1556619 | 0.86 | BACE1 (0.46) | BACE1CDC25BALDH1A1CDC25AMAPT | |
| SCHEMBL22411120 | 0.80 | MAPT (0.53) | BACE1CDC25BALDH1A1CDC25AMAPT | |
| SCHEMBL1556617 | 0.80 | CDC25B (0.60) | CDC25BALDH1A1CDC25AMAPTIDO1 | |
| SCHEMBL6555840 | 0.80 | BACE1 (0.75) | BACE1CDC25BALDH1A1CDC25AMAPT | |
| SCHEMBL8598269 | 0.78 | BACE1 (0.59) | BACE1CDC25BALDH1A1CDC25AMAPT | |
| SCHEMBL11048150 | 0.74 | BACE1 (0.72) | BACE1CDC25BALDH1A1CDC25AMAPT | |
| SCHEMBL8596787 | 0.73 | BACE1 (0.57) | BACE1CDC25BALDH1A1CDC25AMAPT | |
| SCHEMBL9695242 | 0.72 | MAPT (0.61) | CDC25BALDH1A1CDC25AMAPTTP53 | |
| SCHEMBL29673492 | 0.72 | BACE1 (1.00) | BACE1CDC25BALDH1A1CDC25AMAPT | |
| SCHEMBL8596446 | 0.72 | PTPN1 (0.64) | BACE1CDC25BALDH1A1CDC25AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110606936-B | Poly [ norbornene 1, 4-dimethyl dinaphthoquinone ] and preparation method and application thereof | 天津大学 | 2022-03-15 | — | — | CN | disclosed |