Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | APAF1 | O14727 | 2/20 | 0.47 |
| ▸ | TDP2 | O95551 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | BLM | P54132 | 3/20 | 0.44 |
| ▸ | CDC25B | P30305 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598269 | 0.87 | BACE1 (0.59) | BACE1PTPN1APAF1TDP2P2RX7 | |
| SCHEMBL6555840 | 0.78 | BACE1 (0.75) | BACE1PTPN1APAF1TDP2MAPT | |
| SCHEMBL31423340 | 0.73 | BACE1 (1.00) | BACE1PTPN1MAPTMAPK1MEN1 | |
| SCHEMBL29424584 | 0.73 | BACE1 (0.56) | BACE1PTPN1MAPTMAPK1MEN1 | |
| SCHEMBL8596788 | 0.73 | PTPN1 (0.62) | BACE1PTPN1APAF1TDP2MAPT | |
| SCHEMBL312389 | 0.73 | BACE1 (1.00) | BACE1PTPN1MAPTMAPK1MEN1 | |
| SCHEMBL29673492 | 0.71 | BACE1 (1.00) | BACE1PTPN1MAPTMAPK1MEN1 | |
| SCHEMBL8596446 | 0.71 | PTPN1 (0.64) | BACE1PTPN1MAPTMAPK1MEN1 | |
| SCHEMBL5485068 | 0.71 | BACE1 (1.00) | BACE1PTPN1MAPTMAPK1MEN1 | |
| Lawsone SCHEMBL16541 | 0.70 | MAPT (0.68) | BACE1PTPN1APAF1TDP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653441-B1 | Polymer scale preventive agent | SHINETSU CHEMICAL CO (JP) | 1998-02-04 | — | — | EP | disclosed |