Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 9/20 | 0.67 |
| ▸ | XDH | P47989 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31345813 | 0.93 | HSP90AA1 (0.70) | HSP90AA1XDHL3MBTL1POLBCTDSP1 | |
| Catalpol SCHEMBL420515 | 0.88 | HSP90AA1 (0.65) | HSP90AA1XDHL3MBTL1POLBCTDSP1 | |
| Catalpol SCHEMBL17231369 | 0.88 | HSP90AA1 (0.65) | HSP90AA1XDHL3MBTL1POLBCTDSP1 | |
| Catalpol SCHEMBL29374095 | 0.88 | HSP90AA1 (0.65) | HSP90AA1XDHL3MBTL1POLBCTDSP1 | |
| SCHEMBL29478493 | 0.82 | HSP90AA1 (0.59) | HSP90AA1XDHL3MBTL1POLBCTDSP1 | |
| SCHEMBL20382966 | 0.82 | HSP90AA1 (0.55) | HSP90AA1XDHL3MBTL1POLBCTDSP1 | |
| Catalposide SCHEMBL419598 | 0.81 | HSP90AA1 (1.00) | HSP90AA1XDHL3MBTL1POLBCTDSP1 | |
| SCHEMBL20714336 | 0.80 | HSP90AA1 (0.55) | HSP90AA1XDHL3MBTL1POLBCTDSP1 | |
| Picroside Ii SCHEMBL24209283 | 0.79 | HSP90AA1 (0.78) | HSP90AA1XDHL3MBTL1POLBCTDSP1 | |
| Picroside Ii SCHEMBL30387354 | 0.79 | HSP90AA1 (0.78) | HSP90AA1XDHL3MBTL1POLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3409766-B1 | AN ESTERASE THAT IS CAPABLE OF CONVERTING IRIDOIDS AND SECO-IRIDOIDS | N ZYME BIOTEC GMBH (DE) | 2022-03-09 | — | — | EP | disclosed |