Catalpol

Catalpol

SCHEMBL29374095

OC[C@H]1OC(O[C@@H]2OC=C[C@H]3[C@H](O)[C@@H]4O[C@]4(CO)[C@@H]23)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ HSP90AA1 P07900 9/20 0.65
▸ XDH P47989 1/20 0.64
▸ L3MBTL1 Q9Y468 1/20 0.52
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ POLB P06746 1/20 0.42
▸ CTDSP1 Q9GZU7 1/20 0.42
▸ KDM4E B2RXH2 1/20 0.37
▸ GLA P06280 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ SYNJ2 O15056 1/20 0.36
▸ PTPN1 P18031 1/20 0.35
▸ TYR P14679 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Catalpol SCHEMBL17231369 1.00 HSP90AA1 (0.65) HSP90AA1XDHL3MBTL1MEN1KMT2A
Catalpol SCHEMBL420515 1.00 HSP90AA1 (0.65) HSP90AA1XDHL3MBTL1MEN1KMT2A
SCHEMBL29478493 0.94 HSP90AA1 (0.59) HSP90AA1XDHL3MBTL1MEN1KMT2A
SCHEMBL31345813 0.91 HSP90AA1 (0.70) HSP90AA1XDHL3MBTL1MEN1KMT2A
SCHEMBL20714336 0.91 HSP90AA1 (0.55) HSP90AA1XDHL3MBTL1MEN1KMT2A
SCHEMBL20382966 0.91 HSP90AA1 (0.55) HSP90AA1XDHL3MBTL1MEN1KMT2A
Methylcatalpol SCHEMBL29425882 0.88 HSP90AA1 (0.67) HSP90AA1XDHL3MBTL1MEN1KMT2A
SCHEMBL10307818 0.85 L3MBTL1 (0.53) HSP90AA1XDHL3MBTL1MEN1KMT2A
Catalposide SCHEMBL419598 0.79 HSP90AA1 (1.00) HSP90AA1XDHL3MBTL1MEN1KMT2A
SCHEMBL20382967 0.78 HSP90AA1 (0.43) HSP90AA1XDHL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113834881-B Callicarpa nudiflora identification method 海南九芝堂药业有限公司 2023-10-31 — — CN claimed
EP-4635569-A2 METHODS OF DELIVERING A NEUROPROTECTIVE POLYPEPTIDE TO THE CENTRAL NERVOUS SYSTEM Peptron, Inc. (KR) 2025-10-22 — — EP disclosed
US-12207653-B2 Carrier system for preparing herbaceous extracts SISAF LIMITED (GB) 2025-01-28 — — US disclosed
EP-4493205-A1 A LOW MOLECULAR WEIGHT COMPOUND FOR USE IN THE TREATMENT OF SPINOCEREBELLAR ATAXIA TYPE 3 Instytut Chemii Bioorganicznej Polskiej Akademii Nauk (PL) 2025-01-22 — — EP disclosed
EP-3946270-B1 CARRIER SYSTEM FOR PREPARING HERBACEOUS EXTRACTS SISAF LTD (GB) 2024-08-14 — — EP disclosed
CN-113834881-B Callicarpa nudiflora identification method 海南九芝堂药业有限公司 2023-10-31 — — CN disclosed
US-11771657-B2 Methods of delivering a neuroprotective polypeptide to the central nervous system THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-10-03 — — US disclosed
WO-2023177314-A1 A LOW MOLECULAR WEIGHT COMPOUND FOR USE IN THE TREATMENT OF SPINOCEREBELLAR ATAXIA TYPE 3 INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK (PL) 2023-09-21 — — WO disclosed
EP-4188075-A1 NUTRIENT LOSS REDUCTION METHOD, USES AND PRODUCTS PGG Wrightson Seeds Limited (NZ) 2023-06-07 — — EP disclosed
US-20220265563-A1 METHODS OF DELIVERING A NEUROPROTECTIVE POLYPEPTIDE TO THE CENTRAL NERVOUS SYSTEM PEPTRON, INC. (KR) 2022-08-25 — — US disclosed
US-20220174952-A1 CARRIER SYSTEM FOR PREPARING HERBACEOUS EXTRACTS SISAF LIMITED (GB) 2022-06-09 — — US disclosed
CN-110198721-B Antibacterial composition containing polyvinylpyrrolidone and sodium dimercaptopropanesulfonate and application thereof 梅迪德创新研发有限公司 2022-06-07 — — CN disclosed
US-11273130-B2 Methods of delivering a neuroprotective polypeptide to the central nervous system The United States, as represented by the Secretary Department of Health and Human Services (US) 2022-03-15 — — US disclosed
EP-3585422-B1 ANTISEPTIC COMPOSITION COMPRISING UNITHIOL AND DIMETHYLSULFOXIDE, USE OF THE COMPOSITION AND METHOD OF WOUND TREATMENT WITH ITS USE MEDID INNOVATION DEV LTD (CY) 2022-02-09 — — EP disclosed
EP-3585399-B1 ANTISEPTIC COMPOSITION COMPRISING POLYVINYLPYRROLIDONE AND UNITHIOL AND USE OF THE COMPOSITION MEDID INNOVATION DEV LTD (CY) 2022-02-09 — — EP disclosed
WO-2022025774-A1 NUTRIENT LOSS REDUCTION METHOD, USES AND PRODUCTS PGG WRIGHTSON SEEDS LIMITED (NZ) 2022-02-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220265563-A1 METHODS OF DELIVERING A NEUROPROTECTIVE POLYPEPTIDE TO THE CENTRAL NERVOUS SYSTEM GLP1R, IAPP, BDNF HSP90AA1 709/4885XDH 3482/4885L3MBTL1 1960/4885
US-11273130-B2 Methods of delivering a neuroprotective polypeptide to the central nervous system GLP1R, IAPP, BDNF HSP90AA1 709/4885XDH 3482/4885L3MBTL1 1960/4885
US-12207653-B2 Carrier system for preparing herbaceous extracts FUCA2, HPSE, ALG1 HSP90AA1 581/4885XDH 4480/4885L3MBTL1 4785/4885
US-20220174952-A1 CARRIER SYSTEM FOR PREPARING HERBACEOUS EXTRACTS FUCA2, HPSE, ALG1 HSP90AA1 581/4885XDH 4480/4885L3MBTL1 4785/4885
US-11771657-B2 Methods of delivering a neuroprotective polypeptide to the central nervous system GLP1R, IAPP, BDNF HSP90AA1 709/4885XDH 3482/4885L3MBTL1 1960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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