Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tarenninoside D SCHEMBL29426111 | 0.87 | PRKCA (0.46) | PRKCAPTPN1ELANESNCACYP19A1 | |
| Tarenninoside G SCHEMBL29426145 | 0.80 | PTPN1 (0.47) | PTPN1MAPTJUN | |
| Tarennin SCHEMBL29425925 | 0.77 | HSP90AA1 (0.50) | PRKCAPTPN1ELANEHSP90AA1SNCA | |
| Tarenninoside C SCHEMBL29426155 | 0.76 | XDH (0.52) | PTPN1MAPTJUN | |
| SCHEMBL15438013 | 0.74 | SNCA (0.64) | PRKCAPTPN1KDM1ABACE1SNCA | |
| Ixoside SCHEMBL29474997 | 0.74 | MAPT (0.63) | PTPN1MAPT | |
| SCHEMBL15711514 | 0.74 | SNCA (0.66) | PRKCAPTPN1KDM1ABACE1SNCA | |
| SCHEMBL20944781 | 0.74 | SNCA (0.66) | PRKCAPTPN1KDM1ABACE1SNCA | |
| SCHEMBL546975 | 0.74 | SNCA (0.66) | PRKCAPTPN1KDM1ABACE1SNCA | |
| SCHEMBL29426143 | 0.73 | PRKCA (0.52) | PRKCAPTPN1ELANEHSP90AA1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3409766-B1 | AN ESTERASE THAT IS CAPABLE OF CONVERTING IRIDOIDS AND SECO-IRIDOIDS | N ZYME BIOTEC GMBH (DE) | 2022-03-09 | — | — | EP | disclosed |