Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 10/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29516847 | 0.81 | POLB (0.46) | STAT3POLBCTDSP1MAPTMEN1 | |
| SCHEMBL29594415 | 0.68 | HSP90AA1 (0.61) | STAT3POLBCTDSP1MAPTMEN1 | |
| SCHEMBL29425853 | 0.67 | MAPT (0.48) | STAT3POLBCTDSP1MAPTMEN1 | |
| SCHEMBL29426172 | 0.66 | MAPT (0.54) | STAT3MAPT | |
| SCHEMBL29375702 | 0.61 | LGALS8 (0.47) | — | |
| SCHEMBL19499656 | 0.61 | LGALS8 (0.47) | — | |
| SCHEMBL9058007 | 0.60 | POLB (0.46) | STAT3POLBCTDSP1MAPTMEN1 | |
| SCHEMBL29425960 | 0.59 | POLB (0.53) | STAT3POLBCTDSP1MAPTMEN1 | |
| SCHEMBL16351477 | 0.58 | IGF2R (0.43) | STAT3MAPTMEN1KMT2A | |
| SCHEMBL1984501 | 0.57 | CD69 (0.48) | STAT3MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3409766-B1 | AN ESTERASE THAT IS CAPABLE OF CONVERTING IRIDOIDS AND SECO-IRIDOIDS | N ZYME BIOTEC GMBH (DE) | 2022-03-09 | — | — | EP | disclosed |