Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF2R | P11717 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LGALS8 | O00214 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.41 |
| ▸ | LGALS4 | P56470 | 2/20 | 0.41 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.41 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.41 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.41 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16044953 | 0.91 | LGALS8 (0.44) | IGF2RL3MBTL1LGALS8MEN1KMT2A | |
| SCHEMBL2489957 | 0.88 | LGALS3 (0.48) | IGF2RL3MBTL1LGALS8MEN1KMT2A | |
| SCHEMBL15441204 | 0.88 | LGALS8 (0.41) | IGF2RL3MBTL1LGALS8MEN1KMT2A | |
| SCHEMBL21924090 | 0.87 | LGALS8 (0.40) | LGALS8LGALS3LGALS4LGALS9LGALS1 | |
| SCHEMBL1984501 | 0.86 | CD69 (0.48) | IGF2RL3MBTL1LGALS8MEN1KMT2A | |
| SCHEMBL15441203 | 0.86 | LGALS8 (0.42) | IGF2RL3MBTL1LGALS8LGALS3LGALS4 | |
| SCHEMBL2492336 | 0.86 | LGALS3 (0.43) | IGF2RL3MBTL1LGALS8MEN1KMT2A | |
| SCHEMBL15128960 | 0.86 | L3MBTL1 (0.49) | L3MBTL1LGALS8MAPTSLC28A3 | |
| SCHEMBL28341510 | 0.86 | L3MBTL1 (0.49) | L3MBTL1LGALS8MAPTSLC28A3 | |
| SCHEMBL22452303 | 0.82 | TLR4 (0.45) | L3MBTL1MEN1KMT2AMAPTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10899879-B2 | Biodegradable trehalose glycopolymers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-01-26 | — | — | US | disclosed |
| EP-3180023-B1 | BIODEGRADABLE TREHALOSE GLYCOPOLYMERS | UNIV CALIFORNIA (US) | 2020-02-19 | — | — | EP | disclosed |
| US-10543280-B2 | Stabilization of biomolecules using sugar polymers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-01-28 | — | — | US | disclosed |
| US-20190125885-A1 | STABILIZATION OF BIOMOLECULES USING SUGAR POLYMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-05-02 | — | — | US | disclosed |
| US-10273333-B2 | Substituted polyesters by thiol-ene modification: rapid diversification for therapeutic protein stabilization | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-04-30 | — | — | US | disclosed |
| US-20180312630-A1 | BIODEGRADABLE TREHALOSE GLYCOPOLYMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-11-01 | — | — | US | disclosed |
| EP-3342796-A1 | SUBSTITUTED POLYESTERS BY THIOL-ENE MODIFICATION: RAPID DIVERSIFICATION FOR THERAPEUTIC PROTEIN STABILIZATION | The Regents of The University of California (US) | 2018-07-04 | — | — | EP | disclosed |
| US-20180112034-A1 | SUBSTITUTED POLYESTERS BY THIOL-ENE MODIFICATION: RAPID DIVERSIFICATION FOR THERAPEUTIC PROTEIN STABILIZATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-04-26 | — | — | US | disclosed |
| US-9901648-B2 | Stabilization of biomolecules using sugar polymers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-02-27 | — | — | US | disclosed |
| US-9901648-B2 | Stabilization of biomolecules using sugar polymers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-02-27 | — | — | US | disclosed |
| EP-3180023-A1 | BIODEGRADABLE TREHALOSE GLYCOPOLYMERS | The Regents of The University of California (US) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016025668-A1 | BIODEGRADABLE TREHALOSE GLYCOPOLYMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-18 | — | — | WO | disclosed |
| US-20140377838-A1 | STABILIZATION OF BIOMOLECULES USING SUGAR POLYMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-12-25 | — | — | US | disclosed |
| US-20140377838-A1 | STABILIZATION OF BIOMOLECULES USING SUGAR POLYMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180112034-A1 | SUBSTITUTED POLYESTERS BY THIOL-ENE MODIFICATION: RAPID DIVERSIFICATION FOR THERAPEUTIC PROTEIN STABILIZATION | TREH, MGAM, TRRAP | IGF2R 25/4885L3MBTL1 206/4885LGALS8 411/4885 |
| US-10899879-B2 | Biodegradable trehalose glycopolymers | TREH, B3GAT3, MGAM | IGF2R 27/4885L3MBTL1 489/4885LGALS8 90/4885 |
| US-10273333-B2 | Substituted polyesters by thiol-ene modification: rapid diversification for therapeutic protein stabilization | TREH, MGAM, TRRAP | IGF2R 25/4885L3MBTL1 206/4885LGALS8 411/4885 |
| US-20180312630-A1 | BIODEGRADABLE TREHALOSE GLYCOPOLYMERS | TREH, B3GAT3, MGAM | IGF2R 21/4885L3MBTL1 518/4885LGALS8 90/4885 |
| US-10543280-B2 | Stabilization of biomolecules using sugar polymers | TREH, HBG1, SMURF1 | IGF2R 1254/4885L3MBTL1 2349/4885LGALS8 469/4885 |
| US-20190125885-A1 | STABILIZATION OF BIOMOLECULES USING SUGAR POLYMERS | TREH, HBG1, SMURF1 | IGF2R 1254/4885L3MBTL1 2349/4885LGALS8 469/4885 |
| US-20140377838-A1 | STABILIZATION OF BIOMOLECULES USING SUGAR POLYMERS | TREH, HBG1, SMURF1 | IGF2R 1254/4885L3MBTL1 2349/4885LGALS8 469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.