Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 3/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25333361 | 0.91 | AR (0.48) | ARALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29428881 | 0.91 | ALDH1A1 (0.44) | ARALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25334978 | 0.84 | ALDH1A1 (0.47) | ARALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14102883 | 0.79 | TDP1 (0.39) | ALDH1A1TDP1KMT2AERN1TRIM24 | |
| SCHEMBL25333287 | 0.79 | ERN1 (0.41) | TDP1MAPTERN1TRIM24TYR | |
| SCHEMBL25332470 | 0.78 | ALDH1A1 (0.46) | ARALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25334376 | 0.77 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL25333318 | 0.76 | ERN1 (0.47) | ALDH1A1CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL14662307 | 0.74 | SOS1 (0.44) | ALDH1A1CYP1A2CYP2C9CYP2C19TDP1 | |
| SCHEMBL14662079 | 0.74 | KMO (0.42) | ALDH1A1CYP1A2CYP2C9CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116234550-B | Aromatic formyl substituted tricyclic compound and preparation method and application thereof | 劲方医药科技(上海)股份有限公司 | 2024-12-27 | — | — | CN | disclosed |
| WO-2022063101-A1 | AROYL SUBSTITUTED TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2022-03-31 | — | — | WO | disclosed |